SDC4 antibody

Catalog No. ABIN317791

Product Details anti-SDC4 Antibody

Target: SDC4 (Syndecan 4 (SDC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of Syndecan-4 protein.(region surrounding Lys175)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SDC4

Target: SDC4 (Syndecan 4 (SDC4))

Alternative Name: Syndecan-4 (SDC4) (SDC4 Products)

Synonyms: SYND4 antibody, AA959608 antibody, AW108331 antibody, Synd4 antibody, ryudocan antibody, syndecan-4 antibody, RATRYUDOCA antibody, RYUDOCA antibody, SDC4 antibody, sdc4l antibody, wu:fc47g09 antibody, Syndecan-4 antibody, amphiglycan antibody, syn-4 antibody, syn4 antibody, syndecan 4 antibody, syndecan 4 S homeolog antibody, syndecan 4 L homeolog antibody, SDC4 antibody, Sdc4 antibody, sdc4 antibody, sdc4.S antibody, sdc4.L antibody

Background: Syndecans are type I integral membrane proteoglycans that contain both chondroitin sulfate and heparan sulfate groups. Syndecans are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 (SYND1, also called CD138) is an 85-92 kDa extracellular matrix receptor, which binds to Collagens, Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 (also designated N-Syndecan) interact with MK (midkine), a growth/differentiation factor invloved in embryogenesis of the central nervous system. Syndecan-2 (also designated Fibroglycan) is highly expressed at areas of high morphogenetic activity, such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 (also designated Amphiglycan or Ryudocan) functions cooperatively with integrins in the processes of cell spreading, focal adhesion assembly and actin stress fiber assembly.Synonyms: Amphiglycan, Ryudocan core protein, SYND4

Molecular Weight: approx. 22 kDa

Gene ID: 6385

NCBI Accession: NP_002990

UniProt: P31431

Pathways: Glycosaminoglycan Metabolic Process