KIR5.1 antibody

Catalog No. ABIN317797

Product Details anti-KIR5.1 Antibody

Target: KIR5.1 (KCNJ16) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 16 (KCNJ16))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIR5.1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Kir5.1 antibody detects endogenous levels of Kir5.1 protein.(region surrounding asn410)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KIR5.1

Target: KIR5.1 (KCNJ16) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 16 (KCNJ16))

Alternative Name: KCNJ16 (KCNJ16 Products)

Synonyms: kcnj16-A antibody, Kir5.1 antibody, KCNJ16 antibody, BIR9 antibody, KIR5.1 antibody, 6430410F18Rik antibody, AI132396 antibody, potassium channel, inwardly rectifying subfamily J, member 16 S homeolog antibody, potassium voltage-gated channel subfamily J member 16 antibody, potassium channel, inwardly rectifying subfamily J, member 16 antibody, potassium inwardly-rectifying channel, subfamily J, member 16 antibody, kcnj16.S antibody, KCNJ16 antibody, kcnj16 antibody, Kcnj16 antibody

Background: The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as KIR1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as KIR1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Down's syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas. The gene encoding human KIR5.1 maps to chromosome 17.Synonyms: Inward rectifier K(+) channel Kir5.1, Inward rectifier potassium channel 16, KCNJ16, Potassium channel, inwardly rectifying subfamily J member 16

Molecular Weight: approx. 48 kDa

Gene ID: 3773

NCBI Accession: NP_061128

UniProt: Q9NPI9