FGF22 antibody

Catalog No. ABIN317810

Product Details anti-FGF22 Antibody

Target: FGF22 (Fibroblast Growth Factor 22 (FGF22))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF22 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: FGF-22 antibody detects endogenous levels of FGF-22 protein. (region surrounding Ala96)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FGF22

Target: FGF22 (Fibroblast Growth Factor 22 (FGF22))

Alternative Name: FGF22 (FGF22 Products)

Synonyms: si:dkey-21e2.2 antibody, si:dkeyp-74c5.3 antibody, 2210414E06Rik antibody, FGF-22 antibody, fibroblast growth factor 22 antibody, FGF22 antibody, fgf22 antibody, Fgf22 antibody

Background: Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. Fibroblast growth factor-22 (FGF-22) is a secreted protein whose gene is localized to human chromosome 19p13.3. FGF-22 is expressed preferentially in the inner root sheath of the hair follicle, suggesting that it is important in hair development.Synonyms: FGF-22, Fibroblast growth factor 22

Molecular Weight: approx. 20 kDa

Gene ID: 27006

NCBI Accession: NP_065688

UniProt: Q9HCT0

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway