TAS1R3 antibody

Catalog No. ABIN317869

Product Details anti-TAS1R3 Antibody

Target: TAS1R3 (Taste Receptor, Type 1, Member 3 (TAS1R3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAS1R3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificity: T1R3 antibody detects endogenous levels of T1R3 protein.(region surrounding Val365)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TAS1R3

Target: TAS1R3 (Taste Receptor, Type 1, Member 3 (TAS1R3))

Alternative Name: TAS1R3 / T1R3 (TAS1R3 Products)

Synonyms: tas1r3 antibody, T1R3 antibody, Sac antibody, T1r3 antibody, taste receptor, type 1, member 3 antibody, taste 1 receptor member 3 antibody, TAS1R3 antibody, tas1r3 antibody, Tas1r3 antibody

Background: The sense of taste provides animals with valuable information about the quality and nutritional value of food. There are four widely accepted categories of taste perception: sweet, bitter, salty and sour. A controversial fifth taste, known as umami or monosodium glutamate (MSG), has also been described. A family of G protein-coupled receptors are involved in taste perception and include T1R, which is involved in sweet and umami taste perception, and T2R, which is involved in bitter taste perception. The T1R family consists of three members: T1R1, T1R2 and T1R3. These proteins form heterodimers, which alter the selectivity of the subunits. The T1R2 and T1R3 heterodimer functions as a receptor for sweet taste, and recognizes several sweet-tasting molecules such as sucrose, saccharin, dulcin and acesulfame-K. The T1R1 and T1R3 heterodimer recognizes L-amino acids to perceive umami taste. Sweet taste transduction is carried out by two pathways. First, sucrose and other sugars activate Gas via the T1Rs, which activates adenylyl cyclase to generate cAMP.Synonyms: Sweet taste receptor T1R3, TR3, Taste receptor type 1 member 3

Molecular Weight: approx. 93 kDa

Gene ID: 83756

NCBI Accession: NP_689414

UniProt: Q7RTX0