TUBGCP4 antibody

Catalog No. ABIN317908

Product Details anti-TUBGCP4 Antibody

Target: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBGCP4 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: GCP4 antibody detects endogenous levels of GCP4 protein.(region surrounding Leu225)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TUBGCP4

Target: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Alternative Name: TUBGCP4 (TUBGCP4 Products)

Synonyms: RGD1306924 antibody, 76p antibody, MGC81229 antibody, zgc:194561 antibody, zgc:194580 antibody, DKFZp459O2210 antibody, 76P antibody, GCP-4 antibody, GCP4 antibody, h76p antibody, hGCP4 antibody, hGrip76 antibody, 4932441P04Rik antibody, D2Ertd435e antibody, tubulin, gamma complex associated protein 4 antibody, tubulin gamma complex associated protein 4 antibody, tubulin gamma complex associated protein 4 L homeolog antibody, Tubgcp4 antibody, TUBGCP4 antibody, tubgcp4.L antibody, tubgcp4 antibody

Background: The γ-Tubulin complex is composed of γ Tubulin and the γ-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. γ-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the γ-Tubulin complex. GCP4 (γ-Tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the γ-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation.Synonyms: 76P, GCP-4, GCP4, Gamma-ring complex protein 76 kDa, Gamma-tubulin complex component 4, Grip76

Molecular Weight: approx. 76 kDa

Gene ID: 27229

NCBI Accession: NP_055259

UniProt: Q9UGJ1

Pathways: M Phase