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Growth Hormone 1 antibody

GH1 Reactivity: Human, Rat, Dog, Sheep, Cat WB, IF, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN318574
  • Target See all Growth Hormone 1 (GH1) Antibodies
    Growth Hormone 1 (GH1)
    Reactivity
    • 99
    • 18
    • 13
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Rat, Dog, Sheep, Cat
    Host
    • 69
    • 48
    • 2
    • 1
    Rabbit
    Clonality
    • 63
    • 57
    Polyclonal
    Conjugate
    • 77
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Growth Hormone 1 antibody is un-conjugated
    Application
    • 70
    • 54
    • 35
    • 22
    • 20
    • 15
    • 14
    • 13
    • 13
    • 12
    • 9
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody recognizes human Growth Hormone (GH), which acts to control body growth and metabolic activity. In Western blotting a band of approximately 20 kDa is seen using lysates of human pituitary gland.
    Purification
    Purified IgG prepared by affinity chromatography on Protein G
    Immunogen
    Growth hormone from ovine pituitary.
    Isotype
    IgG
    Top Product
    Discover our top product GH1 Primary Antibody
  • Application Notes
    Western blot: 1/50-1/500. Immunofluorescence: 1/10-1/100. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections: 1/500-1/4000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    5.0 mg/mL
    Buffer
    Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Storage in frost-free freezers is not recommended.
  • Target
    Growth Hormone 1 (GH1)
    Alternative Name
    Somatotropin / Growth Hormone / GH1 (GH1 Products)
    Synonyms
    GH antibody, GH-N antibody, GHN antibody, IGHD1B antibody, hGH-N antibody, Gh1 antibody, GH1 antibody, gh antibody, Gh antibody, GH2 antibody, RNGHGP antibody, ghl antibody, gh-n antibody, ghn antibody, ighd1b antibody, gh1 antibody, ghb-A antibody, GHI antibody, GHB3 antibody, growth hormone 1 antibody, growth hormone antibody, somatotropin-like antibody, somatotropin antibody, growth hormone prepeptide antibody, growth hormone 1 L homeolog antibody, growth hormone 1 S homeolog antibody, Somatotropin-1 antibody, GH1 antibody, Gh antibody, GH antibody, LOC100305005 antibody, Gh1 antibody, LOC100534452 antibody, LOC100232594 antibody, LOC100303681 antibody, gh1 antibody, LOC100356068 antibody, LOC100136588 antibody, gh1.L antibody, gh1.S antibody, LOC109081196 antibody
    Background
    Human growth hormone (hGH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. The effects of hGH in the body can be generally described as anabolic. It stimulates amino acid uptake and protein synthesis in muscle and other tissues. Growth Hormone (GH1) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Genes for growth hormone (GH) are found in a gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. The GHN1 gene is transcribed exclusively in the pituitary, whereas the other 4 genes are expressed only in placental tissues. Several isoforms of GH1 exist. Human growth hormone (hGH) is also used as a reporter protein, because it is secreted from mammalian cells it can be assayed by ELISA on culture supernatant using antibodies to determine the level of expression.Synonyms: Growth hormone 1, HGH, Pituitary growth hormone
    Gene ID
    2688
    NCBI Accession
    NP_000506
    UniProt
    P01241
    Pathways
    NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
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