Advanced Glycosylation End Product (AGE) antibody

Antigen: Advanced Glycosylation End Product (AGE)

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: Enzyme Immunoassay (EIA), Western Blotting (WB)

Catalog no.: ABIN318817

Additional Information

Characteristics: Synonyms: Advanced Glycation End Products

Alternative name: AGE

Immunogen: Glycated modified protein.

Cross-Reactivity: Human

Isotype: IgG  (Matching secondary antibodies)

Description: Glycation is the post-translational modification of proteins, linking a reducing sugar to anamino group on a protein. AGEs are thought to be involved in structural and functionalalterations of proteins observed in aging and diabetes. Increases in pentosidine levels areassociated with aging, diabetes, cataracts, renal diseases, chronic rheumatoid arthritis,photaged skin and Alzheimers disease. Carboxymethyllysine is involved in uracemia.

Specificity: This antibody recognizes a variety of advanced glycated end product (AGE) epitopes. AGEs recognized by this antibody include Carboxymethyllysine and Pentosidine. Species: Human. Others not tested. Add. Information: Antiserum Preparation: Antisera to Advanced Glycated End products were raised byrepeated immunisations of Goats with highly purified antigen.

Application Details

Application Notes: ELISA: 1/4000. Western Blot: 1/2000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Purification: Serum

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Research Area: Cancer, Atherosclerosis, Metabolism

Restrictions: For Research Use only