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DFFB antibody (AA 205-222)
DFFB
Reactivity: Mouse
WB, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DFFB Antibody
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Target
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DFFB
(DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
Binding Specificity
All epitopes for DFFB antibodies
AA 205-222
Reactivity
All reactivities for DFFB antibodies
Mouse
Host
All hosts for DFFB antibodies
Rabbit
Clonality
All clonalities for DFFB antibodies
Polyclonal
Conjugate
All conjugates for DFFB antibodies
This DFFB antibody is un-conjugated
Application
All applications for DFFB antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody recognises the 40 kDa CAD in Western blots.
Purification
Affinity Chromatography
Immunogen
Synthetic peptide corresponding to amino acids 205-222 of Mouse CAD
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Western Blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS, 0.02 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for DFFB
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Target
DFFB
(DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
Alternative Name
DFFB / CAD (DFFB Products )
Synonyms
CAD antibody, CPAN antibody, DFF-40 antibody, DFF2 antibody, DFF40 antibody, LOC100223514 antibody, 40kDa antibody, 5730477D02Rik antibody, Didff antibody, Cad antibody, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase antibody, DNA fragmentation factor subunit beta antibody, DNA fragmentation factor, beta polypeptide (caspase-activated DNase) antibody, DNA fragmentation factor, beta subunit antibody, CAD antibody, DFFB antibody, dffb antibody, LOC100223514 antibody, Dffb antibody
Background
CAD (Caspase Activated Deoxyribonuclease) is the murine homologue of human DFF-40. CAD is released and activated by caspase cleavage of ICAD, and eventually causes degradation of nuclear DNA.Synonyms: CPAN, Caspase-activated DNase, Caspase-activated deoxyribonuclease, Caspase-activated nuclease, DFF-40, DFF2, DFF40, DNA fragmentation factor 40 kDa subunit, DNA fragmentation factor subunit beta
Gene ID
13368
NCBI Accession
NP_031885
UniProt
O54788
Pathways
Apoptosis , Caspase Cascade in Apoptosis
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