Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CCR8 antibody (AA 183-201)

CCR8 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN319016
  • Target See all CCR8 Antibodies
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    Binding Specificity
    • 14
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 183-201
    Reactivity
    • 49
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 43
    • 5
    • 4
    • 1
    Rabbit
    Clonality
    • 46
    • 7
    Polyclonal
    Conjugate
    • 33
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR8 antibody is un-conjugated
    Application
    • 35
    • 28
    • 22
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody recognises the chemokine receptor CCR8, also known as CDw198, which has been identified as a co-receptor for HIV infection. CCR8 is a receptor for the human chemokine 1-309 which is expressed on spleen, thymus and T lymphoblastic cell lines. This antibody detects a band of approximately 50 kDa.
    Purification
    Purified
    Immunogen
    Peptide corresponding to amino acids 183 to 201 of human CDw198 (CCR8).
    Isotype
    IgG
    Top Product
    Discover our top product CCR8 Primary Antibody
  • Application Notes
    Western Blot: 1: 500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate buffered saline containing 0.02 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
    Alternative Name
    CDw198 / CCR8 (CCR8 Products)
    Synonyms
    CC-CKR-8 antibody, CCR-8 antibody, CDw198 antibody, CKRL1 antibody, CMKBR8 antibody, CMKBRL2 antibody, CY6 antibody, GPRCY6 antibody, TER1 antibody, C-C antibody, C-C CKR-8 antibody, CKR-8 antibody, Cmkbr8 antibody, mCCR8 antibody, C-C motif chemokine receptor 8 antibody, chemokine (C-C motif) receptor 8 antibody, CCR8 antibody, Ccr8 antibody
    Background
    CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation regulated cytokine (TARC) and macrophage inflammatory protein 1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. CCR8 is also believed to be alternative coreceptor with CD4 for HIV-1 infection.Synonyms: C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR-8, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPR-CY6, TER1
    Gene ID
    1237
    NCBI Accession
    NP_005192
    UniProt
    P51685
You are here:
Support