Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (pThr305) antibody

Details for Product No. ABIN319093
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Antigen
Synonyms CAMKA, PKCCD, PK2CDD, zgc:112538, zgc:123320, camk2, camk2b
Epitope
pThr305
(20), (10), (5), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(70), (51), (37), (8), (6), (5), (5), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(64), (31), (6)
Clonality
Polyclonal
Application
Western Blotting (WB)
(96), (40), (30), (22), (12), (10), (8), (7), (4), (4), (3), (2), (2), (2)
Pubmed 1 reference available
Catalog no. ABIN319093
Quantity 0.1 mL
Price
819.50 $   Plus shipping costs $45.00
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Immunogen Synthetic phosphopeptide corresponding to an amino acid sequence within CAMKII, which includes phosphorylated Thr305.
Isotype IgG
Specificity This antiobdy is specific for calcium/calmodulin kinase II (CAMKII) alpha and CAMKII beta, when phosphorylated at Thr305.
Purification Serum
Alternative Name CAMK2A
Background CAMKII is a multi-functional calcium and calmodulin-dependent kinase which has an important role in cell signalling. Phosphorylation at Thr305 results in inhibition of CAMKII kinase activity.
Alternate names: CAMKA, CaM kinase II subunit alpha, CaM-kinase II alpha chain, CaMK-II subunit alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain, KIAA0968
Gene ID 815
NCBI Accession NP_741960.1
UniProt Q9UQM7
Research Area Kinases/Phosphatases
Application Notes Western Blot: 1: 1000, detects bands of approximately 50 and 60 kDa in rat brain lysatescorresponding to CaMK II alpha and CaMK II beta respectively. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Elgersma, Fedorov, Ikonen et al.: "Inhibitory autophosphorylation of CaMKII controls PSD association, plasticity, and learning." in: Neuron, Vol. 36, Issue 3, pp. 493-505, 2002 (PubMed).

Hosts (64), (31), (6)
Reactivities (70), (51), (37), (8), (6), (5), (5), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1)
Applications (96), (40), (30), (22), (12), (10), (8), (7), (4), (4), (3), (2), (2), (2)
Epitopes (20), (10), (5), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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