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Tryptophan Hydroxylase 1 antibody

TPH1 Reactivity: Human, Rat WB, IHC (fro) Host: Sheep Polyclonal unconjugated
Catalog No. ABIN319127
  • Target See all Tryptophan Hydroxylase 1 (TPH1) Antibodies
    Tryptophan Hydroxylase 1 (TPH1)
    Reactivity
    • 87
    • 48
    • 48
    • 11
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 82
    • 7
    • 5
    Sheep
    Clonality
    • 85
    • 7
    Polyclonal
    Conjugate
    • 47
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Tryptophan Hydroxylase 1 antibody is un-conjugated
    Application
    • 71
    • 41
    • 21
    • 17
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody recognises Tryptophan Hydroxylase (TPH) which catalyses the 5-hydroxylation of tryptophan, in the first stage of indoleamine biosynthesis. Serotonin biosynthesis occurs principally in neurons which originate in the raphe nucleus of the brain, and melatonin synthesis takes place within the pineal gland.
    Purification
    Affinity chromatography
    Immunogen
    Recombinant rabbit Tryptophan Hydroxylase purified from E. coli.
    Isotype
    IgG
    Top Product
    Discover our top product TPH1 Primary Antibody
  • Application Notes
    Immunohistochemistry on frozen sections: 1: 1000. Western Blot: 1: 1000, detects a band of approximately 55 kDa in human dorsal Raphenucleus lysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Tryptophan Hydroxylase 1 (TPH1)
    Alternative Name
    Tryptophan 5-Hydroxylase 1 (TPH1) (TPH1 Products)
    Synonyms
    TPRH antibody, TRPH antibody, tph antibody, tph1 antibody, tphD1 antibody, tph2 antibody, tph1l antibody, tphD2 antibody, Tph antibody, TPH antibody, SERGEF antibody, LOC100229598 antibody, tryptophan hydroxylase 1 antibody, tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a antibody, TryPtophan Hydroxylase antibody, tryptophan hydroxylase 1b antibody, tryptophan hydroxylase 1 L homeolog antibody, tryptophan 5-hydroxylase 1 antibody, TPH1 antibody, tph1a antibody, tph-1 antibody, tph1b antibody, Tph1 antibody, tph1.L antibody, LOAG_02149 antibody, Tsp_05203 antibody
    Background
    Synonyms: TPRH, TRPH, Tryptophan 5-monooxygenase 1
    Gene ID
    7166
    NCBI Accession
    NP_004170
    UniProt
    P17752
    Pathways
    Feeding Behaviour
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