Tryptophan Hydroxylase 1 antibody
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- Target See all Tryptophan Hydroxylase 1 (TPH1) Antibodies
- Tryptophan Hydroxylase 1 (TPH1)
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Reactivity
- Human, Rat
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Host
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Sheep
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Clonality
- Polyclonal
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Conjugate
- This Tryptophan Hydroxylase 1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- This antibody recognises Tryptophan Hydroxylase (TPH) which catalyses the 5-hydroxylation of tryptophan, in the first stage of indoleamine biosynthesis. Serotonin biosynthesis occurs principally in neurons which originate in the raphe nucleus of the brain, and melatonin synthesis takes place within the pineal gland.
- Purification
- Affinity chromatography
- Immunogen
- Recombinant rabbit Tryptophan Hydroxylase purified from E. coli.
- Isotype
- IgG
- Top Product
- Discover our top product TPH1 Primary Antibody
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- Application Notes
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Immunohistochemistry on frozen sections: 1: 1000. Western Blot: 1: 1000, detects a band of approximately 55 kDa in human dorsal Raphenucleus lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Tryptophan Hydroxylase 1 (TPH1)
- Alternative Name
- Tryptophan 5-Hydroxylase 1 (TPH1) (TPH1 Products)
- Synonyms
- TPRH antibody, TRPH antibody, tph antibody, tph1 antibody, tphD1 antibody, tph2 antibody, tph1l antibody, tphD2 antibody, Tph antibody, TPH antibody, SERGEF antibody, LOC100229598 antibody, tryptophan hydroxylase 1 antibody, tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a antibody, TryPtophan Hydroxylase antibody, tryptophan hydroxylase 1b antibody, tryptophan hydroxylase 1 L homeolog antibody, tryptophan 5-hydroxylase 1 antibody, TPH1 antibody, tph1a antibody, tph-1 antibody, tph1b antibody, Tph1 antibody, tph1.L antibody, LOAG_02149 antibody, Tsp_05203 antibody
- Background
- Synonyms: TPRH, TRPH, Tryptophan 5-monooxygenase 1
- Gene ID
- 7166
- NCBI Accession
- NP_004170
- UniProt
- P17752
- Pathways
- Feeding Behaviour
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