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p53 antibody (Tumor Protein P53) (Ser37)

Details for Product anti-TP53 Antibody No. ABIN319307, Supplier: Log in to see
Antigen
  • bbl
  • BCC7
  • bfy
  • bhy
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • LFS1
  • p44
  • P53
  • p53
  • tp53
  • TP53
  • Tp53
  • TpMs
  • Trp53
  • TRP53
  • wu:fb40d06
  • Xp53
  • zgc:111919
Alternatives
anti-Human p53 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
Ser37
141
87
63
54
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39
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27
25
22
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2
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2
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1
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Reactivity
Human
1783
320
269
100
34
21
19
13
11
11
10
10
9
5
4
4
4
3
3
3
2
2
1
Host
Rabbit
1234
654
7
4
3
1
1
Clonality
Polyclonal
Conjugate
This p53 antibody is un-conjugated
61
51
39
33
23
23
17
17
14
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13
6
4
4
4
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3
2
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1
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Application
Western Blotting (WB)
1418
601
529
319
315
307
235
156
101
87
53
39
35
17
16
12
12
11
11
9
4
3
3
3
2
2
2
1
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1
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1
Supplier
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of Serine 37 (L-P-SP-Q-A).
Specificity This antibody detects endogenous levels of total p53 protein.
Purification Immunoaffinity Chromatography.
Alternative Name p53 (TP53) (TP53 Antibody Abstract)
Background Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
Gene ID 7157
NCBI Accession NP_000537
UniProt P04637
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling
Application Notes Western Blot (1/500-1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at-20 °C.
Supplier Images
 image for anti-p53 antibody (Tumor Protein P53) (Ser37) (ABIN319307) anti-Tumor Protein P53 (TP53) (Ser37) antibody
Background publications Solomon, Pasupuleti, Xu, McDonagh, Curtis, DiStefano, Huber: "Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage." in: Molecular and cellular biology, Vol. 26, Issue 1, pp. 28-38, 2005

Cases, de Lorenzo: "The black cat/white cat principle of signal integration in bacterial promoters." in: The EMBO journal, Vol. 20, Issue 1-2, pp. 1-11, 2001

Duboule: "Hox is in the hair: a break in colinearity?" in: Genes & development, Vol. 12, Issue 1, pp. 1-4, 1998