CD4 Molecule (CD4) antibody (Biotin)

Details for Product No. ABIN319659
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Antigen
Synonyms CD4mut, p55, W3/25, L3T4, Ly-4, cd4
Reactivity
Human
(586), (447), (146), (43), (33), (26), (25), (25), (20), (20), (11), (6), (4), (3), (3), (3), (1)
Host
Mouse
(680), (385), (150), (3), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Biotin
(173), (123), (120), (68), (31), (17), (11), (9), (9), (8), (8), (7), (6), (6), (6), (6), (6), (6), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(916), (195), (166), (165), (130), (126), (89), (55), (49), (46), (30), (11), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
Catalog no. ABIN319659
Quantity 25 µg
Price
253.00 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Human PHA blasts. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSI myeloma cell line.
Clone RPA-T4
Isotype IgG1
Specificity This antibody recognises CD4. Epitope mapping studies have shown that antibodies, produced by clone RPA-T4, recognise an epitope within domain 1, of the extracellular region, of the CD4 molecule. Clone RPA-T4 has been reported to block gp120-CD4 interaction and inhibit syncytium formation. We recommend the use of SM1058LE for this purpose.
Purification Affinity chromatography on Protein G
Alternative Name CD4
Background CD4 is a 55kD cell surface glycoprotein that is primarily expressed on a subpopulation of T lymphocytes, on peripheral blood monocytes and on tissue macrophages.
Alternate names: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Gene ID 920
NCBI Accession NP_000607.1
UniProt P01730
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: Use 10 ul of neat-1/10 diluted antibody to label 10e6 cells or 100ul of lysed whole peripheral blood. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Zarkesh-Esfahani, Pockley, Metcalfe et al.: "High-dose leptin activates human leukocytes via receptor expression on monocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 8, pp. 4593-9, 2001 (PubMed).

Voehringer, Koschella, Pircher: "Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1)." in: Blood, Vol. 100, Issue 10, pp. 3698-702, 2002 (PubMed).

Hosts (680), (385), (150), (3), (1)
Reactivities (586), (447), (146), (43), (33), (26), (25), (25), (20), (20), (11), (6), (4), (3), (3), (3), (1)
Applications (916), (195), (166), (165), (130), (126), (89), (55), (49), (46), (30), (11), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Conjugates (173), (123), (120), (68), (31), (17), (11), (9), (9), (8), (8), (7), (6), (6), (6), (6), (6), (6), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (41), (11), (10), (9), (9), (6), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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