anti-CD4 antibody (CD4 Molecule) (Biotin)

Details for Product anti-CD4 Antibody No. ABIN319659
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Antigen
Synonyms cd4, L3T4, Ly-4, CD4mut, W3/25, p55
Reactivity
Human
(1043), (806), (233), (69), (41), (35), (28), (26), (25), (16), (14), (11), (9), (7), (7), (6), (6), (5), (3), (2), (1), (1)
Host
Mouse
(1253), (765), (201), (4), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
This CD4 antibody is conjugated to Biotin
(316), (271), (189), (134), (44), (35), (27), (24), (23), (23), (22), (21), (21), (18), (15), (12), (9), (9), (9), (9), (9), (8), (8), (7), (7), (6), (6), (6), (6), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(1740), (395), (341), (272), (222), (205), (138), (104), (69), (63), (32), (30), (22), (18), (17), (14), (14), (11), (9), (7), (6), (6), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 25 μg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
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Immunogen Human PHA blasts. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSI myeloma cell line.
Clone RPA-T4
Isotype IgG1
Specificity This antibody recognises CD4. Epitope mapping studies have shown that antibodies, produced by clone RPA-T4, recognise an epitope within domain 1, of the extracellular region, of the CD4 Molecule. Clone RPA-T4 has been reported to block gp120-CD4 interaction and inhibit syncytium formation. We recommend the use of SM1058LE for this purpose.
Purification Affinity chromatography on Protein G
Alternative Name CD4 (CD4 Antibody Abstract)
Background CD4 is a 55kD cell surface glycoprotein that is primarily expressed on a subpopulation of T lymphocytes, on peripheral blood monocytes and on tissue macrophages.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Gene ID 920
NCBI Accession NP_000607
UniProt P01730
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: Use 10 μL of neat-1/10 diluted antibody to label 10^6 cells or 100 μL of lysed whole peripheral blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Voehringer, Koschella, Pircher: "Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1)." in: Blood, Vol. 100, Issue 10, pp. 3698-702, 2002 (PubMed).

Zarkesh-Esfahani, Pockley, Metcalfe et al.: "High-dose leptin activates human leukocytes via receptor expression on monocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 8, pp. 4593-9, 2001 (PubMed).

Validation Images
Catalog No. ABIN319659
253.00 $
Plus shipping costs $45.00
Quantity
Price
25 μg
253.00 $

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