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Details for Product No. ABIN319759

Integrin alpha 1 (ITGA1) antibody (Biotin)

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Antigen
Synonyms VLA1, CD49a, Vla1, CD49A, E130012M19Rik
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Biotin
Application
»Alternatives Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN319759
Quantity 25 µg
Price
242.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Clone TS2-7
Isotype IgG1
Specificity This antibody recognises the alpha 1 integrin subunit, which forms the VLA-1 heterodimer in association with the beta 1 integrin.
Purification Affinity chromatography on Protein G
Alternative Name CD49a / ITGA1
Background VLA-1 is a receptor for collagen and laminin, and is expressed by chronically activated T cells, melanoma cells and smooth muscle cells.
Alternate names: CD49 antigen-like family member A, ITGA-1, Integrin alpha-1, Laminin and Collagen Receptor, VLA-1, VLA1
Gene ID 3672
NCBI Accession NP_852478.1
UniProt P56199
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Hemler, Jacobson, Strominger: "Biochemical characterization of VLA-1 and VLA-2. Cell surface heterodimers on activated T cells." in: The Journal of biological chemistry, Vol. 260, Issue 28, pp. 15246-52, 1986 (PubMed).

Hemler, Sanchez-Madrid, Flotte et al.: "Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 132, Issue 6, pp. 3011-8, 1984 (PubMed).

Alternatives for antigen "Integrin alpha 1 (ITGA1)", type "Antibodies"
Hosts (35), (31), (2)
Reactivities (65), (24), (24), (12), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (29), (27), (16), (15), (13), (10), (8), (8), (3), (2), (2), (2), (1), (1), (1)
Conjugates (7), (6), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (3), (2), (2), (2), (1), (1), (1), (1), (1)
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