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Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (FITC)

Details for Product No. ABIN319956, Supplier: Login to see
Antigen
  • NKR-P1
  • KLRB1
  • 4930431A04Rik
  • Gm4696
  • Klrb1g
  • Klrb6
  • Ly-55
  • Ly55
  • NKR-P1G
  • Nkrp-1e
  • Nkrp1g
  • CD161
  • CLEC5B
  • NKR
  • NKR-P1A
  • NKRP1A
  • hNKR-P1A
  • Klrb1d
  • Klrb1f
  • Nkr-p1e
Reactivity
Human
116
60
16
2
2
Host
Mouse
167
23
Clonality (Clone)
Monoclonal ()
Conjugate
FITC
39
30
12
7
5
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
154
44
43
28
17
14
13
11
9
6
4
3
3
3
2
2
1
1
Supplier
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Clone B199-2
Isotype IgG2b
Specificity This antibody recognises the human CD161 cell surface antigen, expressed by almost all NK cells and a small subset of CD3+ve T cells. Clone B199.2 recognises a similar epitope to the DX9 monoclonal antibody.
Purification Protein G chromatography
Alternative Name CD161 / KLRB1 (KLRB1 Antibody Abstract)
Background CD161 is a homodimeric cell surface protein, comprising two chains of 40-44kD.Synonyms: C-type lectin domain family 5 member B, CLEC5B, HNKR-P1a, Killer cell lectin-like receptor subfamily B member 1, NKRP1A, Natural killer cell surface protein P1A
Gene ID 3820
NCBI Accession NP_002249
UniProt Q12918
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways
Application Notes Flow cytometry: neat - 1/10, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4, containing 1 % BSA and 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Azzoni, Zatsepina, Abebe et al.: "Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 7, pp. 3493-500, 1998 (PubMed).

Bennett, Zatsepina, Zamai et al.: "Definition of a natural killer NKR-P1A+/CD56-/CD16- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12." in: The Journal of experimental medicine, Vol. 184, Issue 5, pp. 1845-56, 1996 (PubMed).

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