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CD45 antibody (Protein tyrosine Phosphatase, Receptor Type, C) Biotin

Details for Product anti-PTPRC Antibody No. ABIN320033, Supplier: Login to see New
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Antigen
Reactivity
Human
(1002), (674), (200), (70), (49), (42), (39), (29), (21), (11), (8), (5), (5), (4), (3), (3), (2), (1), (1), (1), (1), (1)
Host
Mouse
(1042), (704), (209), (3), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
This CD45 antibody is conjugated to Biotin
(293), (219), (171), (107), (38), (28), (25), (24), (21), (19), (16), (16), (14), (14), (14), (14), (10), (10), (8), (8), (7), (7), (6), (6), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(1552), (331), (326), (290), (239), (222), (193), (118), (82), (47), (42), (29), (28), (12), (11), (10), (7), (7), (6), (6), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Quantity 25 μg
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Availability
Immunogen Human T Lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Clone F8-11-13
Isotype IgG1
Specificity This antibody recognises the human CD45RA cell surface antigen. Clone F8-11-13 reacts with the high molecular weight form of the leucocyte common antigen (LCA) expressed by B lymphocytes and a subset of T lymphocytes.
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
Alternative Name CD45 / LCA (PTPRC Antibody Abstract)
Background CD45 is a complex molecule existing in a number of isoforms. Antibodies recognising a common epitope on all of these isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.Synonyms: L-CA, Leukocyte common antigen, PTPRC, Receptor-type tyrosine-protein phosphatase C, T200
Gene ID 5788
NCBI Accession NP_002829
UniProt P08575
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody undiluted at -20 °C.
Background publications Franitza, Kollet, Brill et al.: "TGF-beta1 enhances SDF-1alpha-induced chemotaxis and homing of naive T cells by up-regulating CXCR4 expression and downstream cytoskeletal effector molecules." in: European journal of immunology, Vol. 32, Issue 1, pp. 193-202, 2001 (PubMed).

OGrady, Stewart, Lowrey et al.: "CD40 expression in Hodgkin's disease." in: The American journal of pathology, Vol. 144, Issue 1, pp. 21-6, 1994 (PubMed).

Dalchau, Fabre et al.: "Identification with a monoclonal antibody of a predominantly B lymphocyte-specific determinant of the human leukocyte common antigen. Evidence for structural and possible functional diversity of the ..." in: The Journal of experimental medicine, Vol. 153, Issue 4, pp. 753-65, 1981 (PubMed).

Catalog No. ABIN320033

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