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KDM5A antibody (AA 1416-1434)

KDM5A Reactivity: Human WB, IF, FACS Host: Mouse Monoclonal 18E8 unconjugated
Catalog No. ABIN3201015
  • Target See all KDM5A Antibodies
    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
    Binding Specificity
    • 15
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1416-1434
    Reactivity
    • 68
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 62
    • 5
    Mouse
    Clonality
    • 55
    • 13
    Monoclonal
    Conjugate
    • 26
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This KDM5A antibody is un-conjugated
    Application
    • 47
    • 25
    • 17
    • 14
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Specificity
    Specific to human and mouse RBP2. Can detect endogenous levels of RBP2.
    Purification
    Purified
    Sterility
    Sterile filtered
    Immunogen
    A synthetic peptide corresponding to human RBP2, aa 1416-1434.
    Clone
    18E8
    Isotype
    IgG2a kappa
  • Application Notes
    1. Western blotting: ~1 g/mL
    2. Immunofluorescence staining
    3. Flow Cytometry: 1 g for 10^6 cells
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol
    Preservative
    Azide free
    Storage
    -20 °C
  • Lopez-Bigas, Kisiel, Dewaal, Holmes, Volkert, Gupta, Love, Murray, Young, Benevolenskaya: "Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation." in: Molecular cell, Vol. 31, Issue 4, pp. 520-30, (2008) (PubMed).

    Christensen, Agger, Cloos, Pasini, Rose, Sennels, Rappsilber, Hansen, Salcini, Helin: "RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3." in: Cell, Vol. 128, Issue 6, pp. 1063-76, (2007) (PubMed).

    Klose, Yan, Tothova, Yamane, Erdjument-Bromage, Tempst, Gilliland, Zhang, Kaelin: "The retinoblastoma binding protein RBP2 is an H3K4 demethylase." in: Cell, Vol. 128, Issue 5, pp. 889-900, (2007) (PubMed).

  • Target
    KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
    Alternative Name
    KDM5A (KDM5A Products)
    Synonyms
    Jarid1a antibody, JARID1A antibody, RBBP-2 antibody, RBBP2 antibody, RBP2 antibody, AA409370 antibody, C76986 antibody, Rbbp2 antibody, lysine demethylase 5A antibody, lysine (K)-specific demethylase 5A antibody, Kdm5a antibody, KDM5A antibody
    Background
    RBP2 was originally identified as a retinoblastoma binding protein. It is also known as JARID1A (Jumonji, AT rich interactive domain 1A). RBP2 plays both negative and positive roles in RB- mediated transcriptional activation, depending on the kinds of genes and regulates differentiation by its function as an H3K4 histone demethylase.
    UniProt
    P29375
    Pathways
    Chromatin Binding, Warburg Effect
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