Intercellular Adhesion Molecule 2 (ICAM2) antibody (Biotin)

Details for Product No. ABIN320226
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Antigen
Synonyms ICAM2, CD102, Icam-2, Ly-60
Reactivity
Human
(121), (77), (15)
Host
Mouse
(65), (60), (57), (2)
Clonality (Clone)
Monoclonal ()
Conjugate
Biotin
(29), (23), (11), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(125), (56), (51), (45), (31), (25), (18), (11), (10), (6), (4), (3), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 25 µg
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Catalog No. ABIN320226
253.00 $
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Immunogen Transfected COS cells expressing ICAM-2 cDNA. Cells from immunised BALB/c mice were fused with cells of the Murine P3X63Ag.653 myeloma cell line.
Clone CBRIC2-2
Isotype IgG2a
Specificity This antibody recognises CD102, also known as intercellular adhesion molecule-2 (ICAM-2). Clone CBR-IC2/2 is reported to inhibit interactions between CD102 and LFA-1. We recommend the use of SM2223LE for this purpose.
Purification Affinity Chromatography on Protein G.
Alternative Name CD102 / ICAM2
Background CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is strongly expressed by endothelial cells. CD102 interacts with the CD11a/CD1
Alternate names: ICAM-2, Intercellular adhesion molecule 2
Gene ID 3384
NCBI Accession NP_000864
UniProt P13598
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: Use 10 ul of the suggested working dilution to label 10e6 cells in 100 ul. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications de Fougerolles, Stacker, Schwarting et al.: "Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1." in: The Journal of experimental medicine, Vol. 174, Issue 1, pp. 253-67, 1991 (PubMed).

Diacovo, deFougerolles, Bainton et al.: "A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2." in: The Journal of clinical investigation, Vol. 94, Issue 3, pp. 1243-51, 1994 (PubMed).

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