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Tissue factor antibody (FITC)
F3
Reactivity: Human
FACS
Host: Mouse
Monoclonal
CLB-TF-5
FITC
Product Details anti-Tissue factor Antibody (FITC)
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Target
See all Tissue factor (F3) Antibodies
Tissue factor (F3)
(Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
Reactivity
All reactivities for Tissue factor antibodies
Human
Host
All hosts for Tissue factor antibodies
Mouse
Clonality
All clonalities for Tissue factor antibodies
Monoclonal
Conjugate
All conjugates for Tissue factor antibodies
This Tissue factor antibody is conjugated to FITC
Application
All applications for Tissue factor antibodies
Flow Cytometry (FACS)
Specificity
This antibody recognises CD142. The CLB/TF-5 antibody has been used successfully in an ELISA assay as a coating antibody in association with clone CLB/TF-1 (Cat.-No AM01050PU-N), which recognises a different epitope of CD142.
Purification
Affinity Chromatography on Protein A from tissue culture supernantant.
Clone
CLB-TF-5
Isotype
IgG1
Top Product
Discover our top product F3 Primary Antibody
Alternatives
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anti-Coagulation Factor III (thromboplastin, Tissue Factor) (F3) (AA 32-100) antibody
F3
Reactivity: Human, Mouse, Rat, Pig
WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.1 mg/mL
Buffer
Tris buffered saline, pH 8.0 containing, 0.09 % Sodium Azide, 1 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
References for anti-Tissue factor antibody (FITC) (ABIN320295)
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Rancourt, Veress, Guo, Jones, Hendry-Hofer, White : "Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide. " in: American journal of physiology. Lung cellular and molecular physiology , Vol. 302 , Issue 1 , pp. L82-92 , (2012 ) (PubMed ).
Target Details for Tissue factor
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Target
Tissue factor (F3)
(Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
Alternative Name
CD142 / Tissue Factor (F3 Products )
Synonyms
CD142 antibody, TF antibody, TFA antibody, PRO1557 antibody, PRO2086 antibody, TFQTL1 antibody, f3 antibody, AA409063 antibody, Cf-3 antibody, Cf3 antibody, tf antibody, zgc:112151 antibody, coagulation factor III, tissue factor antibody, transferrin antibody, coagulation factor IIIa antibody, coagulation factor III antibody, tissue factor antibody, coagulation factor IIIb antibody, coagulation factor III (thromboplastin, tissue factor) S homeolog antibody, F3 antibody, TF antibody, f3a antibody, tf antibody, f3b antibody, f3.S antibody
Background
CD142 is a 45kD cell surface glycoprotein which is otherwise known as Tissue Factor (TF). CD142 expression can be induced on monocytes, macrophages and endothelial cells by various stimuli including interleukin 1, tumour necrosis factor and endotoxin. CD142 initiates the blood clotting cascade by binding coagulation factor VIIa, which activates factor IX or factor X by specific limited proteolysis. CD142 also plays an important role in inflammation, angiogenesis, and the pathophysiology of atherosclerosis and cancer.Synonyms: Coagulation factor III, F3, TF, Thromboplastin
Gene ID
2152
NCBI Accession
NP_001984
UniProt
P13726
Pathways
Positive Regulation of Endopeptidase Activity , Smooth Muscle Cell Migration , Platelet-derived growth Factor Receptor Signaling
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