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SHC1 antibody (AA 371-420)

SHC1 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Monkey, Guinea Pig, Rabbit, Xenopus laevis, Bat, Hamster WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6738705
  • Target See all SHC1 Antibodies
    SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
    Binding Specificity
    • 28
    • 22
    • 20
    • 19
    • 12
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 371-420
    Reactivity
    • 165
    • 124
    • 86
    • 9
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Horse, Pig, Monkey, Guinea Pig, Rabbit, Xenopus laevis, Bat, Hamster
    Host
    • 151
    • 21
    Rabbit
    Clonality
    • 150
    • 22
    Polyclonal
    Conjugate
    • 77
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    This SHC1 antibody is un-conjugated
    Application
    • 147
    • 56
    • 38
    • 25
    • 18
    • 14
    • 14
    • 14
    • 13
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    Human SHC1
    Predicted Reactivity
    Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig, Xenopus (100%).
    Purification
    Immunoaffinity purified
    Immunogen
    Synthetic peptide located between aa371-420 of human SHC1 (P29353, NP_003020). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Zebra finch, Xenopus (100%), Galago, Turkey, Chicken, Stickleback, Zebrafish (92%), Panda (85%).

    Type of Immunogen: Synthetic peptide
    Isotype
    IgG
    Top Product
    Discover our top product SHC1 Primary Antibody
  • Application Notes
    Approved: WB

    Usage: ELISA titer using peptide based assay: 1:312500. Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Distilled Water.
    Concentration
    Lot specific
    Buffer
    Lyophilized from PBS with 2 % sucrose
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Target
    SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1))
    Alternative Name
    p66 / SHC (SHC1 Products)
    Synonyms
    SHC1 antibody, SHC antibody, SHCA antibody, P66shc antibody, si:dkey-246i14.4 antibody, wu:fc10h03 antibody, shc antibody, p66shc antibody, Shc antibody, ShcA antibody, p66 antibody, SHC adaptor protein 1 antibody, Shc1p antibody, squalene--hopene cyclase antibody, SHC (Src homology 2 domain containing) transforming protein 1 antibody, SHC (Src homology 2 domain containing) transforming protein 1 L homeolog antibody, src homology 2 domain-containing transforming protein C1 antibody, SHC1 antibody, shc1 antibody, Shc1 antibody, shc1.L antibody
    Background
    Name/Gene ID: SHC1

    Synonyms: SHC1, p46 shc, p52 shc, SH2 domain protein C1, p66, SHCA, SHC, SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A
    Gene ID
    6464
    NCBI Accession
    NP_003020
    UniProt
    P29353
    Pathways
    RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, ER-Nucleus Signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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