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IL-6 Receptor antibody

IL6R Reactivity: Human WB, ELISA, FACS, Neut Host: Mouse Monoclonal 17506 unconjugated
Catalog No. ABIN6774202
  • Target See all IL-6 Receptor (IL6R) Antibodies
    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
    Reactivity
    • 49
    • 19
    • 16
    Human
    Host
    • 47
    • 22
    • 5
    • 1
    • 1
    Mouse
    Clonality
    • 50
    • 25
    • 1
    Monoclonal
    Conjugate
    • 49
    • 13
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-6 Receptor antibody is un-conjugated
    Application
    • 51
    • 23
    • 22
    • 21
    • 12
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Neutralization (Neut)
    Specificity
    Recognizes human IL-6R.
    Purification
    Protein G purified
    Immunogen
    Sf 21-derived rhIL-6R.

    Type of Immunogen: Recombinant protein
    Clone
    17506
    Isotype
    IgG1
    Top Product
    Discover our top product IL6R Primary Antibody
  • Application Notes
    Approved: ELISA, Flo (25 μg/mL), Neut, WB (1 - 2 μg/mL)

    Usage: Suitable for use in Neutralization, Western Blot, ELISA and Flow Cytometry. Neutralization of Human IL6 R Bioactivity: ~0.1-0.2 μg/mL in the presence of 20 ng/mL of rhIL-6 R and 20 ng/mL of rhIL-6, using the M1 cell line. Western Blot: 1-2 μg/mL, The detection limit is ~100 ng/lane under non-reducing and reducing conditions. ELISA Capture: 2-8 μg/mL. Use biotinylated human IL-6 R detection antibody and recombinant human IL-6 R as the standard. Flow Cytometry: 25 μg/mL, 10 μL labels 1-2.5x10^5 U937 cells in a total reaction volume <200 μL.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Sterile PBS
    Concentration
    Lot specific
    Buffer
    Lyophilized, PBS, 5 % trehalose
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target
    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
    Alternative Name
    IL6R / IL6 Receptor (IL6R Products)
    Synonyms
    IL6R antibody, il-6ra antibody, CD126 antibody, IL-6R-1 antibody, IL-6RA antibody, IL6Q antibody, IL6RA antibody, IL6RQ antibody, gp80 antibody, IL6R1 antibody, Il6ra antibody, IL-6Ralpha antibody, IL-6R antibody, Il6r antibody, interleukin 6 receptor antibody, interleukin 6 receptor, alpha antibody, IL6R antibody, il6r antibody, Il6r antibody, Il6ra antibody
    Background
    Name/Gene ID: IL6R
    Family: Interleukin

    Synonyms: IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ
    Gene ID
    3570
    UniProt
    P08887
    Pathways
    JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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