USP11 antibody

Catalog No. ABIN334288

Product Details anti-USP11 Antibody

Target: USP11 (Ubiquitin Specific Peptidase 11 (USP11))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP11 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Partial peptide of Mouse Usp11

Application Details

Application Notes: IHC: 5.0-10 ug/mL (Paraffin embedded Sections)

Restrictions: For Research Use only

Handling

Concentration: 0.25 mg/ml

Buffer: PBS [containing 2 % Block Ace as a stabilizer, 0.1 %Proclin as a bacteriostat]

Preservative: ProClin

Storage: -20 °C

Target Details for USP11

Target: USP11 (Ubiquitin Specific Peptidase 11 (USP11))

Alternative Name: Usp11 (USP11 Products)

Synonyms: USP11 antibody, DKFZp459L098 antibody, UHX1 antibody, 6230415D12Rik antibody, mKIAA4085 antibody, Uhx1 antibody, ubiquitin specific peptidase 11 antibody, universal stress protein antibody, USP11 antibody, RR_RS19935 antibody, Usp11 antibody

Background: Usp11 (ubiquitin specific peptidase 11) possesses Cys box, His box, Asp and KRF domains, which are highly conserved in many ubiquitin-specific proteases. Usp11 is a ubiquitous protein in various tissues and is primarily localized in the nucleus of non-dividing cells. Usp11 binds specifically to RanBPM which is a RanGTP-binding protein required for correct nucleation of microtubles and inhibits its ubiquitination and degradation. It has been also shown that Usp11 is involved in regulation of the TNFalpha-induced IKKalpha --> p53 signaling pathway and that Usp11 functions in stabilizing HPV-16E7 by reducing ubiquitination and attenuating E7 degradation. Alternate Names: MGC6649, KIAA4085, mKIAA4085, 6230415D12Rik, Usp11 ubiquitin specific peptidase 11.

Gene ID: 236733