anti-Usp11 antibody

Overview

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	Antigen:	Usp11
	Clonality:	Polyclonal
	Application:	Immunohistochemistry (IHC)
	Reactivity:	Mouse (Murine)
	Host:	Rabbit
	Quantity:	25 ug (0.25 mg/ml)
	Price:	819,43 $ (Plus shipping costs and VAT, Invoice in EUR)
	Order number:	ABIN334288
	Availability:	Ships within 5 to 10 Business Days

Antigen	Usp11
Gene ID	236733
Immunogen	Partial peptide of Mouse Usp11
Reactivity	Mouse (Murine)
Clonality	Polyclonal
Format	Affinitiy-purified
Description	Usp11 (ubiquitin specific peptidase 11) possesses Cys box, His box, Asp and KRF domains, which are highly conserved in many ubiquitin-specific proteases. Usp11 is a ubiquitous protein in various tissues and is primarily localized in the nucleus of non-dividing cells. Usp11 binds specifically to RanBPM which is a RanGTP-binding protein required for correct nucleation of microtubles and inhibits its ubiquitination and degradation. It has been also shown that Usp11 is involved in regulation of the TNFalpha-induced IKKalpha --> p53 signaling pathway and that Usp11 functions in stabilizing HPV-16E7 by reducing ubiquitination and attenuating E7 degradation. Alternate Names: MGC6649, KIAA4085, mKIAA4085, 6230415D12Rik, Usp11 ubiquitin specific peptidase 11.
Host	Rabbit

Application	Immunohistochemistry (IHC) » Click here to view 1 available protocol!
Application Notes	IHC: 5.0-10 ug/mL (Paraffin embedded Sections)
Concentration	0.25 mg/ml
Buffer	PBS [containing 2 % Block Ace as a stabilizer, 0.1 %Proclin as a bacteriostat]
Storage	Store below -20
Research Area	Enzymes
Restrictions	For Research Use only