Arginine Vasopressin Receptor 1B (AVPR1B) antibody

Antigen: Arginine Vasopressin Receptor 1B (AVPR1B)

Synonyms: AVPR3, AVPR1B, LOC443050, si:ch211-125a15.3, VIBR, VPR3, V3/V1b

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN334355

Additional Information

Alternative name: AVPR1B

Gene ID: 553

Immunogen: Peptide with sequence C-PRDLELADGEGTAE, from the C-Terminus of the protein sequence according to NP_000698.1

Description: All names and symbols: AVPR1B, arginine vasopressin receptor 1B, AVPR3, antidiuretic hormone receptor 1B, arginine vasopressin receptor 3, pituitary vasopressin receptor 3, vasopressin V1B receptor. Official Symbol: AVPR1B. RefSeq number(s): NP_000698.1.

Specificity: Expected from sequence similarity: Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Approx. 170kDa band observed in Human Brain (Substantia Nigra) lysates (calculated MW of 47.0kDa according to NP_000698.1). The observed molecular weight corresponds to findings with EB08786, a product of different design reacting to the Mouse protein. Recommended concentration: 0.05-0.2µg/ml. Immunohistochemistry: In paraffin embedded Human Pituitary shows bright cytoplasm staining of a few active secretory cells in the anterior pituitary. Recommended concentration, 5-10µg/ml.

Concentration: 100µg specific antibody in 200µl

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Neurology

Restrictions: For Research Use only

Publications

Publications: Dempster, Burcescu, Wigg et al.: "Evidence of an association between the vasopressin V1b receptor gene (AVPR1B) and childhood-onset mood disorders." in: Archives of general psychiatry, Vol. 64, Issue 10, pp. 1189-95, 2007 (PubMed).