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LAG1 Homolog, Ceramide Synthase 5/6 (LASS5/6) antibody
| Antigen | LAG1 Homolog, Ceramide Synthase 5/6 (LASS5/6) |
| Synonyms | Trh4, CerS5, FLJ25304, MGC45411, LASS5, trh4, MGC159488 |
| Clonality | Polyclonal |
| Host |
Goat |
| Application |
ELISA
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1 reference available |
| Catalog no. | ABIN334429 |
| Quantity | 100 ug |
| Price | 369.20 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 5 Business Days |
Additional Information
| Alternative name | LASS5+6 / CerS5+6 |
| Gene ID | 91012, 25, 71949 (mouse) |
| Immunogen | C-RGKVSKDDRSDVES |
| Description | All names and symbols: LASS5, LAG1 homolog, ceramide synthase 5, CerS5, FLJ25304, MGC45411, Trh4, LAG1 longevity assurance homolog 5. Official Symbol: LASS5. RefSeq number(s): NP_671723.1, NP_982288.1 |
| Specificity | This antibbody is expected to cross-react with the highly similar LASS6. Human, Mouse, Rat, Dog, Cow |
Application Details
| Application Notes | Peptide ELISA: antibody detection limit dilution 1:4,000. Western Blot: Preliminary experiments gave an approx. 60kDa band in lysates of HEK293, HeLa and HepG2 after 0.5µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 45.8kDa according to NP_671723.1. The 60kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported? |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Restrictions | For Research Use only |
Publications
| Publications |
Min, Mesika, Sivaguru et al.: "(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1." in: Molecular cancer research : MCR, Vol. 5, Issue 8, pp. 801-12, 2007 (PubMed).
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