DROSHA antibody (Internal Region)

Catalog No. ABIN334479

Product Details anti-DROSHA Antibody

Target: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This DROSHA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: RNASEN / Drosha

Sequence: KQTDKQKLAQ RE

Specificity: This antibody also cross-reacts with human Ribonuclease III (GeneID 29102, NP_037367.2).

Cross-Reactivity: Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: C-KQTDKQKLAQRE

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 150-160 kDa band observed in Human Liver lysates (calculated MW of 151 kDa according to NP_081075.2). Recommended concentration: 0.3-1 μg/mL. Primary incubation was 1 hour. Preliminary testing was unsuccessful on Mouse and Rat Liver for

Peptide ELISA: antibody detection limit dilution 1:16000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for DROSHA

Target: DROSHA (Drosha, Ribonuclease Type III (DROSHA))

Alternative Name: RNASEN (DROSHA Products)

Synonyms: im:7150667 antibody, zgc:158612 antibody, ETOHI2 antibody, HSA242976 antibody, RANSE3L antibody, RN3 antibody, RNASE3L antibody, RNASEN antibody, 1110013A17Rik antibody, AI874853 antibody, Etohi2 antibody, Rn3 antibody, Rnasen antibody, RGD1307626 antibody, ribonuclease type III, nuclear antibody, Ribonuclease 3 antibody, ribonuclease 3 antibody, drosha ribonuclease III antibody, drosha, ribonuclease type III antibody, rnasen antibody, Thicy_0885 antibody, Sinme_0866 antibody, Isova_2087 antibody, Sphch_0770 antibody, DROSHA antibody, Drosha antibody

Background: Rnasen, Drosha, ribonuclease III, nuclear , 1110013A17Rik, AI874853, Etohi2, MGC115770, Rn3 , ethanol induced 2, ribonuclease III

Gene ID: 29102, 14000, 310159

NCBI Accession: NP_081075

Pathways: Regulatory RNA Pathways