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Details for Product No. ABIN334503

TAR DNA Binding Protein (TARDBP) (Internal Region) antibody

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Antigen
Synonyms ALS10, TDP-43, Tdp43, C85084, 1190002A23Rik, wu:fb77f02, wu:fc52g10, TARDBP, TDP43, DKFZp459I2127, tardbp
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Human, Mouse (Murine)
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Methode Type Peptide ELISA
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN334503
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-HISNAEPKHNSNRQ, from the internal region of the protein sequence according to NP_031401.1.
Cross-Reactivity Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name TARDBP
Background Synonyms: TARDBP, TAR DNA binding protein, ALS10, TDP-43, OTTHUMP00000002171, TAR DNA-binding protein-43
Gene ID 23435, 230908
NCBI Accession NP_031401.1
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA, Hormones, Cytokines
Application Notes ELISA: antibody detection limit dilution 1:16000.
Western blot: Approx. 45 kDa band observed in lysates of cell lines Jurkat and NIH3T3 (calculated MW of 44.7 kDa according to NP_031401.1). A slightly larger protein is detected in some regions of the brain. Recommended concentration: 0.3-1 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Zhang, Xu, Dickey et al.: "Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 39, pp. 10530-4, 2007 (PubMed).

Alternatives for antigen "TAR DNA Binding Protein (TARDBP)", type "Antibodies"
Hosts (89), (24), (5), (1)
Reactivities (115), (67), (48), (34), (19), (19), (17), (17), (5), (3), (1)
Applications (104), (49), (21), (21), (20), (20), (10), (3), (3), (1), (1)
Conjugates (4), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (18), (13), (9), (7), (6), (6), (3), (3), (2), (1), (1), (1)
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