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Secreted Amyloid Protein Precursor (sAPP) (KPI domain 1-4) antibody

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Antigen
Epitope
KPI domain 1-4
Reactivity
Human
1
Host
Rabbit
1
Clonality
Polyclonal
Application
ELISA
1
Supplier
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Immunogen Synthetic peptide of secreted Amyloid protein precursor(sAPP) 1-4
Specificity It does react with sAPP and KPI-domain of its molecular structure, determined by ELISA. The antibody binding to sAPP molecule was verified by Western blotting as well.
Alternative Name secreted Amyloid protein precursor (sAPP) (KPI domain) 1-4
Restrictions For Research Use only
Format Liquid
Buffer Antiserum, having 0.1% NaN3 as preservatives
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -80 °C
Background publications Miyazaki, Hasegawa, Funahashi, Umeda: "A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor." in: Nature, Vol. 362, Issue 6423, pp. 839-41, 1993 (PubMed).

Tanzi, McClatchey, Lamperti, Villa-Komaroff, Gusella, Neve: "Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease." in: Nature, Vol. 331, Issue 6156, pp. 528-30, 1988 (PubMed).

Ponte, Gonzalez-DeWhitt, Schilling, Miller, Hsu, Greenberg, Davis, Wallace, Lieberburg, Fuller: "A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors." in: Nature, Vol. 331, Issue 6156, pp. 525-7, 1988 (PubMed).

Kitaguchi, Takahashi, Tokushima, Shiojiri, Ito: "Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity." in: Nature, Vol. 331, Issue 6156, pp. 530-2, 1988 (PubMed).