Interleukin 12 (IL12) antibody

Antigen: Interleukin 12 (IL12)

Synonyms: CLMF, NKSF, CLMF2, NKSF2, IL-12B, IL12A, p40, Il-12b, Il12p40, Il-12p40, Il12, IL12B, IL-12p40, IL-12, il12b, IL-12 p40, MGC152789, il12p40.b, zgc:152789, IL-12.p40, Il12b, LOC100217488

Clonality: Monoclonal (NYRmIL-12p40)

Host: Rat

Reactivity: Mouse (Murine)

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN334750

Additional Information

Alternative name: Interleukin-12p40

Immunogen: recombinant Murine IL-12 p4

Isotype: IgG2a  (Matching secondary antibodies)

Clone: NYRmIL-12p40

Description: Active IL-12 is a p70 disulphide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by antigen presenting cells and has multiple effects on T lymphocytes and natural killer cells in terms of stimulating cytotoxicity, proliferation, production of other cytokines and Th1 subset differentiation. Synonyms: NKSF2, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40), TSF, Edodekin-alpha, IL-12 p40, IL-12B, IL-12 subunit p40, NK cell stimulatory factor chain 2.

Application Details

Application Notes: By direct ELISA, 1:5,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).

Concentration: 1mg/ml in PBS (after reconstitution)

Purification: Ion exchange

Storage: Shipping Condition: Antibody is shipped lyophilized at ambient temperature. Storage: In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. Reconstitution: Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C.

Research Area: Cytokines, Receptors, Inflammation

Restrictions: For Research Use only