Vascular Endothelial Growth Factor (VEGF) antibody

Antigen: Vascular Endothelial Growth Factor (VEGF)

Synonyms: vegf-A, VEGF, DmVEGF-1, EP1624, PVF, PVF1, PVFs, VEGF2-B, Vegf17E, Vegf17e-a, Vegf17e-b, l(1)G0146, vegf1, DmelCG7103, CG7103, DmVEGF-2, PV2, PVF2, VEGF-2, VEGF27Cb, DmelCG13780, CG13780, CG13781, CG13782, CG13783, CG31629, CG4492, DmVEGF-3, PVF3, VEGF27Ca, DmelCG34378, CG34378, vegf, LOC100033839

Clonality: Monoclonal (NYRhVEGF)

Host: Mouse

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN334759

Additional Information

Alternative name: Vascular Endothelial Growth Factor

Immunogen: recombinant HumanVEGF

Isotype: IgM  (Matching secondary antibodies)

Clone: NYRhVEGF

Description: Vascular endothelial growth factor is an important signaling protein involved in both vasculogenesis and angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells ).VEGF mediates increased vascular permeability, induces angiogenesis, vasculogenesis and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Synonyms: Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609.

Synonyms: vegf-A, VEGF, DmVEGF-1, EP1624, PVF, PVF1, PVFs, VEGF2-B, Vegf17E, Vegf17e-a, Vegf17e-b, l(1)G0146, vegf1, DmelCG7103, CG7103, DmVEGF-2, PV2, PVF2, VEGF-2, VEGF27Cb, DmelCG13780, CG13780, CG13781, CG13782, CG13783, CG31629, CG4492, DmVEGF-3, PVF3, VEGF27Ca, DmelCG34378, CG34378, vegf, LOC100033839

Application Details

Application Notes: By direct ELISA, 1:10,000 dilution will yield 0.15 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).

Concentration: 1mg/ml in PBS (after reconstitution)

Purification: Boric acid precipitation

Storage: Shipping Condition: Antibody is shipped lyophilized at ambient temperature. Storage: In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. Reconstitution: Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C.

Research Area: Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Signaling

Restrictions: For Research Use only