»
Antibodies
»
anti-Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antig...
Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; alpha Polypeptide) (ITGAL) antibody
| Antigen |
|
| Synonyms |
CD11A, LFA-1, LFA1A, Cd11a, Ly-15, Ly-21, ITGAL, CD11a |
| Clonality |
Monoclonal (MCD11a) |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
 Alternatives Blocking Antibody (Inhibition), Immunohistochemistry (IHC), Functional Studies (Func)
|
| Catalog no. |
ABIN334766 |
| Quantity |
500ug (1mg/ml in PBS (after reconstitution...) (Variants) |
| Price |
500.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 5 Business Days |
|
Alternative name
|
CD11a
|
|
Immunogen
|
Enriched mouse peritoneal macrophages
|
|
Isotype
|
IgG2b
|
|
Clone
|
MCD11a
|
|
Description
|
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Synonyms: Integrin, alpha L, CD11A, p180, alpha polypeptide, ITGAL, LFA-1, LFA1A.
|
|
Application Notes
|
Staining and blocking antibody. For staining, use 10 ul/106 cells. This antibody will block signaling through the CD11a molecule. Titer for blocking should be determined by the investigator.
|
|
Concentration
|
1mg/ml in PBS (after reconstitution)
|
|
Purification
|
Ion exchange column
|
|
Storage
|
Storage: Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C.
|
|
Research Area
|
Stem Cells, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; alpha Polypeptide) (ITGAL)", type "Antibodies"
|
Hosts
|
Mouse (58), Rat (37)
|
|
Reactivities
|
Human (42), Mouse (Murine) (39), Rat (Rattus) (7), Cow (Bovine) (3), Rabbit (3), Dog (Canine) (2), Pig (Porcine) (2)
|
|
Applications
|
Flow Cytometry (FACS) (79), Immunoprecipitation (IP) (20), Functional Studies (Func) (12), Immunohistochemistry (Frozen Sections) (IHC (fro)) (7), Immunohistochemistry (IHC) (4), Blocking Antibody (Inhibition) (3), Immunocytochemistry (ICC) (2), Immunofluorescence (IF) (2), Western Blotting (WB) (1)
|
|
Conjugates
|
FITC (20), Biotin (13), PE (10), RPE (7), APC (4), PE,Cy7 (2), Alexa Fluor 488 (1), Alexa Fluor 700 (1), Pacific Blue (1)
|
