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Antibodies
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anti-V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) antibody
V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) antibody
| Antigen |
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| Synonyms |
MRTL, c-Myc, bHLHe39, MYC, CMYC, MGC138120, c-myc, C-MYC, LOC100136746 |
| Clonality |
Monoclonal (NYRhc-myc) |
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Host
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Reactivity
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Application
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Western Blotting (WB) (163), Immunohistochemistry (IHC) (55), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (41), Immunoprecipitation (IP) (41), Enzyme Immunoassay (EIA) (35), Immunofluorescence (IF) (34), ELISA (32), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Flow Cytometry (FACS) (15), Immunocytochemistry (ICC) (11), Dot Blot (Dot) (7), Transfected cell culture (TCC) (6), ELISA (Detection) (1)
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| Catalog no. |
ABIN334809 |
| Quantity |
500ug (1mg/ml in PBS (after reconstitution...) (Variants) |
| Price |
500.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 Business Days |
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Alternative name
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c-Myc
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Immunogen
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synthetic peptides
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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NYRhc-myc
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Description
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C-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. Synonyms: MYC, CMYC, C-MYS, V-MYC, P64.
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Application Notes
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By Western blot 1:2,000 dilution will yield a strong band in WB. Additional Information: This antibody was produced in BALB/c mice
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Concentration
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1mg/ml in PBS (after reconstitution)
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Purification
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Protein A
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Storage
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Storage: Antibody is shipped lyophilized at ambient temperature. In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. Reconstitution: Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C.
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Research Area
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Cancer, Cell Cycle, Transcription Factors
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Restrictions
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For Research Use only
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Alternatives for antigen "V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC)", type "Antibodies"
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Hosts
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Rabbit (134), Mouse (49), Chicken (9), Goat (3), Sheep (3), Rat (1)
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Reactivities
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Human (156), Mouse (Murine) (79), Rat (Rattus) (75), All Species (9), Tag (4), Virus (3), Bird (Avian) (2), Chicken (2)
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Applications
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Western Blotting (WB) (163), Immunohistochemistry (IHC) (55), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (41), Immunoprecipitation (IP) (41), Enzyme Immunoassay (EIA) (35), Immunofluorescence (IF) (34), ELISA (32), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Flow Cytometry (FACS) (15), Immunocytochemistry (ICC) (11), Dot Blot (Dot) (7), Transfected cell culture (TCC) (6), ELISA (Detection) (1)
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Conjugates
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HRP (15), FITC (8), Biotin (2), Alkaline Phosphatase (AP) (1), PE (1)
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Epitopes
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EQKLISEEDL (13), pThr358 (11), pSer373 (10), pSer62 (8), pThr58 (7), c Myc tag (4), S373 (2), T58 (2), C-Term (1), N-Term (1), S62 (1), T358 (1), pT358 (1), pThr373 (1), pThr58,pSer62 (1), pThr58/pSer62 (1)
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Alternatives 
