Selectin E (SELE) antibody

Antigen: Selectin E (SELE)

Synonyms: ELAM, ESEL, CD62E, ELAM1, LECAM2, SELE

Clonality: Monoclonal (HCD62E)

Host: Mouse

Reactivity: Human

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN334818

Additional Information

Alternative name: E-Selectin

Immunogen: Purified, Activated T-Cells

Isotype: IgG1  (Matching secondary antibodies)

Clone: HCD62E

Description: E-Selectin belongs to a family of divalent cation-dependent carbohydrate-binding glycoproteins or adhesion molecules. CD62E is expressed on the surface of endothelial cells and mediates the interaction of leukocytes and platelets with endothelial cells during an inflammatory response. CD62E is found in cytokine-stimulated endothelial cells and is accountable for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It demonstrates structural features such as the existence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. E-Selectin participates in the interaction between leukocytes and the endothelium and appears to be involved in the pathogenesis of atherosclerosis. Synonyms: E-selectin, Endothelial leukocyte adhesion molecule 1, ELAM-1, Leukocyte-endothelial cell adhesion molecule 2, LECAM2, CD62E antigen, SELE, ELAM1, ELAM, ESEL, CD62E.

Application Details

Application Notes: Staining antibody. For staining, use 10ul/106 cells.

Purification: Ion exchange column

Storage: Storage: Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C.

Research Area: CD Antigens, Inflammation, Cancer, Immunology

Restrictions: For Research Use only