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Antibodies
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anti-Interleukin 1, beta (IL1B) antibody
Interleukin 1, beta (IL1B) antibody
| Antigen |
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| Synonyms |
IL-1, IL1F2, IL1-BETA, IL1B, IL-1BETA, MGC111873, zgc:111873, IL-1B |
| Clonality |
Monoclonal (NYR-hIL1beta) |
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Host
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Reactivity
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Application
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 Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Western Blotting (WB) (66), Enzyme Immunoassay (EIA) (43), ELISA (33), Functional Studies (Func) (13), Immunohistochemistry (Frozen Sections) (IHC (fro)) (13), Immunohistochemistry (IHC) (11), Immunoprecipitation (IP) (9), ELISA (Detection) (6), Flow Cytometry (FACS) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Neutralization (Neut) (5), ELISA (Capture) (4), Immunofluorescence (IF) (4), Dot Blot (Dot) (2), Radioimmunoassay (RIA) (2), Blocking Antibody (Inhibition) (1), Immunocytochemistry (ICC) (1), Intracellular Staining (IS) (1)
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| Catalog no. |
ABIN334822 |
| Quantity |
500ug (Variants) |
| Price |
500.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 Business Days |
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Alternative name
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IL-1 beta
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Immunogen
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recombinant Human IL-1b
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Isotype
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IgG2b (Matching secondary antibodies)
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Clone
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NYR-hIL1beta
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Description
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Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. Synonyms: Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF), IL1F2, IL-1 beta.
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Application Notes
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By direct ELISA, 1:20,000 dilution will yield >1.0 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). 1:2,000 dilution will completely inhibit a thymocyte co-stimulation assay using suboptimal doses of concanavalin A.
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Purification
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Ion Exchange
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Storage
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Shipping Condition: Antibody is shipped lyophilized at ambient temperature. Storage: In lyophilized form, for long periods, store at 4(C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20(C. Reconstitution: Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4(C.
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Research Area
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Cytokines, Immunology, Virology, Inflammation, Cancer
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Restrictions
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For Research Use only
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Alternatives for antigen "Interleukin 1, beta (IL1B)", type "Antibodies"
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Hosts
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Mouse (53), Rabbit (50), Goat (2), Rat (2), Sheep (2), Armenian Hamster (1)
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Reactivities
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Human (67), Mouse (Murine) (16), Rat (Rattus) (12), Cow (Bovine) (5), Sheep (Ovine) (4), Monkey (2), Chicken (1), Goat (1), Pig (Porcine) (1), Rabbit (1)
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Applications
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Western Blotting (WB) (66), Enzyme Immunoassay (EIA) (43), ELISA (33), Functional Studies (Func) (13), Immunohistochemistry (Frozen Sections) (IHC (fro)) (13), Immunohistochemistry (IHC) (11), Immunoprecipitation (IP) (9), ELISA (Detection) (6), Flow Cytometry (FACS) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Neutralization (Neut) (5), ELISA (Capture) (4), Immunofluorescence (IF) (4), Dot Blot (Dot) (2), Radioimmunoassay (RIA) (2), Blocking Antibody (Inhibition) (1), Immunocytochemistry (ICC) (1), Intracellular Staining (IS) (1)
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Conjugates
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Biotin (12), FITC (5), HRP (1)
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Epitopes
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Cleaved-Asp210 (2)
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