Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) antibody

Antigen: Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2)

Synonyms: C3DR, CD21, SLEB9

Clonality: Monoclonal (HCD21)

Host: Mouse

Reactivity: Human

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN334824

Additional Information

Alternative name: CD21

Immunogen: Purified human B-Cells

Isotype: IgG2a  (Matching secondary antibodies)

Clone: HCD21

Description: CD21 is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Synonyms: Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CD21 antigen, CR2, C3DR, CD21, SLEB9.

Application Details

Application Notes: Staining antibody. For staining, use 10ul/106 cells. Available Conjugates: This antibody is also available conjugated to biotin and FITC. For staining with biotin or FITC-conjugated antibody use 5-10ul/106 cells.

Purification: Protein-A

Storage: Storage: Lyophilized: store at 4(C. After reconstitution, if not intended for use within a month, aliquot and store at -20(C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4(C.

Research Area: CD Antigens, Surface Receptors of Immune Cells

Restrictions: For Research Use only