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Antibodies
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anti-Integrin alpha M (ITGAM) antibody (FITC)
Integrin alpha M (ITGAM) antibody (FITC)
| Antigen |
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| Synonyms |
CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6, MGC117044, CR3, MAC1, Cd11b, Ly-40, Mac-1, Mac-1a, CD11b/CD18, F730045J24Rik, ITGAM, Itgam |
| Clonality |
Monoclonal (MCD11b) |
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Host
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Reactivity
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Human (108), Mouse (Murine) (90), Rat (Rattus) (19), Rabbit (18), Monkey (10), Cow (Bovine) (8), Dog (Canine) (6), Goat (4), Primates (3), Sheep (Ovine) (3), Cat (Feline) (1), Horse (Equine) (1), Pig (Porcine) (1)
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Conjugate
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FITC (36), PE (24), Biotin (22), APC (7), RPE (4), SPRD (4), APC,Cy7 (3), Cy5 (2), PE,Cy7 (2), Alexa Fluor 647 (1), Alexa Fluor 700 (1), PE,Cy5 (1), PE,DY647 (1), PE-Dyomics 647 (1), RPE,Cy5 (1)
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Application
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 Alternatives Blocking Antibody (Inhibition), Immunohistochemistry (IHC), Functional Studies (Func)
Flow Cytometry (FACS) (169), Immunohistochemistry (Frozen Sections) (IHC (fro)) (50), Immunoprecipitation (IP) (50), Western Blotting (WB) (15), Functional Studies (Func) (14), Immunohistochemistry (IHC) (13), Blocking Antibody (Inhibition) (12), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Enzyme Immunoassay (EIA) (5), Immunocytochemistry (ICC) (3), ELISA (2), Immunofluorescence (IF) (2), Radioimmunoassay (RIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1)
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| Catalog no. |
ABIN334848 |
| Quantity |
500ug (1mg/ml in PBS (after reconstitution...) (Variants) |
| Price |
630.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 Business Days |
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Alternative name
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CD11b
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Immunogen
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Purified mouse LN CD4+ T cells
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Isotype
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IgG2b
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Clone
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MCD11b
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Description
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Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Integrin alpha-m/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. CD-11b is identical with cr-3, the receptor for the ic3b fragment of the third complement component. CD-11b probably recognizes the r-g-d peptide in c3b. Integrin alpha-m/beta-2 is also a receptor for fibrinogen, factor x and icam1. it recognizes p1 and p2 peptides of fibrinogen gamma chain. Synonyms: Integrin, alpha M, CR3A, MO1A, CD11B, MAC-1, MAC1A, MGC117044, ITGAM.
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Application Notes
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Staining and blocking antibody. For staining, use 10 ul/106 cells. This antibody will block signaling through the CD11a molecule. Titer for blocking should be determined by the investigator Available Conjugates: This antibody is only available conjugated to FITC.
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Concentration
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1mg/ml in PBS (after reconstitution)
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Purification
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Ion exchange column
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Storage
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Storage: Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4°C.
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Research Area
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Stem Cells, Hematopoietic Progenitors, Hematopoietic Stem Cells, Glia marker, CD Antigens, Surface Receptors of Immune Cells
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Restrictions
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For Research Use only
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Alternatives for antigen "Integrin alpha M (ITGAM)", type "Antibodies"
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Hosts
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Mouse (104), Rat (87), Rabbit (8), Goat (6)
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Reactivities
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Human (108), Mouse (Murine) (90), Rat (Rattus) (19), Rabbit (18), Monkey (10), Cow (Bovine) (8), Dog (Canine) (6), Goat (4), Primates (3), Sheep (Ovine) (3), Cat (Feline) (1), Horse (Equine) (1), Pig (Porcine) (1)
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Applications
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Flow Cytometry (FACS) (169), Immunohistochemistry (Frozen Sections) (IHC (fro)) (50), Immunoprecipitation (IP) (50), Western Blotting (WB) (15), Functional Studies (Func) (14), Immunohistochemistry (IHC) (13), Blocking Antibody (Inhibition) (12), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Enzyme Immunoassay (EIA) (5), Immunocytochemistry (ICC) (3), ELISA (2), Immunofluorescence (IF) (2), Radioimmunoassay (RIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1)
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Conjugates
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FITC (36), PE (24), Biotin (22), APC (7), RPE (4), SPRD (4), APC,Cy7 (3), Cy5 (2), PE,Cy7 (2), Alexa Fluor 647 (1), Alexa Fluor 700 (1), PE,Cy5 (1), PE,DY647 (1), PE-Dyomics 647 (1), RPE,Cy5 (1)
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