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CD8a Molecule (CD8A) antibody (Biotin)

Antigen

CD8a Molecule (CD8A)
Synonyms CD8, MAL, p32, Leu2, Ly-2, Ly-B, Ly-35, Lyt-2, BB154331, MGC136643, zgc:136643, cd8, LOC100136450
Clonality Monoclonal (NYRmCD8)
Host
Reactivity
Alternatives

Mouse (Murine)
Conjugate
Alternatives Biotin
Application
Alternatives Blocking Antibody (Inhibition), Immunohistochemistry (IHC)
Catalog no. ABIN334876
Quantity 500ug  (Variants)
Price 630.00 $   Plus shipping costs $35.00
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Additional Information
Application Details Alternatives Variants back to top

Alternative name CD8
Immunogen Purified Mouse LN T cells
Isotype IgM
Clone NYRmCD8
Description CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains bind to class-I MHC molecules alpha-3 domains. Synonyms: CD8, MAL, p32.

Application Details
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Application Notes Blocking and staining antibody. For staining, use 10ul/106 cells. Titer for blocking T cell activation should be determined by the investigator. Available Conjugates: This antibody is only available unconjugated and conjugated to FITC.
Purification Ion Exchange Column
Storage Storage: Lyophilized: store at 4(C. After reconstitution, if not intended for use within a month, aliquot and store at -20(C. Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. Stability / Shelf Life: Two years lyophilized, one month in solution at 4(C.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only

Alternatives
Application Details Variants back to top

Alternatives for antigen "CD8a Molecule (CD8A)", type "Antibodies"
Hosts Mouse (311), Rat (105), Rabbit (82)
Reactivities Human (289), Mouse (Murine) (120), Rat (Rattus) (50), Cat (Feline) (21), Chicken (19), Dog (Canine) (14), Pig (Porcine) (13), Cow (Bovine) (12), Monkey (10), Sheep (Ovine) (10), Horse (Equine) (8), Rabbit (8), Guinea Pig (5), Turkey (5), Goat (4), Duck (1)
Applications Flow Cytometry (FACS) (388), Immunohistochemistry (Frozen Sections) (IHC (fro)) (131), Immunoprecipitation (IP) (76), Immunofluorescence (IF) (55), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (51), Western Blotting (WB) (43), ELISA (33), Immunohistochemistry (IHC) (20), Immunocytochemistry (ICC) (15), Functional Studies (Func) (7), Cytotoxicity Test (CyTox) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Blocking Antibody (Inhibition) (5), Enzyme Immunoassay (EIA) (5), Immunoelectron Microscopy (IEM) (3), ELISA (Detection) (2), To be determined by user (TBD) (1)
Conjugates FITC (84), Biotin (46), PE (41), APC (17), RPE (12), Cy5 (9), PE,Cy7 (6), PE,Cy5 (5), SPRD (5), Alexa Fluor 488 (4), HRP (4), PE,Cy5.5 (4), APC,Cy7 (3), Alexa Flour 488 (3), Alexa Fluor 647 (3), Cy3 (3), Cy5,PE (3), Cy5.5 (3), Cy7 (3), Gold (3), PE,Cy3 (3), Pacific Blue (3), RBITC (3), Alexa Fluor 350 (2), Alexa Fluor 555 (2), PE,Texas Red (TR) (2), PerCP (2), APC,Cy5.5 (1), Alexa Fluor 700 (1), Cy5.5,PE (1), Cy7,PE (1), PE,DY590 (1), PE,DY647 (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1), RPE,Cy5 (1), RPE,Cy5.5 (1), RPE,Cy7 (1)
Epitopes C-Term (1), N-Term (1)