Hepatitis C Virus NS3 antibody

Antigen: Hepatitis C Virus NS3

Clonality: Polyclonal

Host: Mouse

Application: ELISA, Immunofluorescence (IF), Western Blotting (WB)

Catalog no.: ABIN335064

Additional Information

Immunogen: Recombinant HCV NS-3 (genotype 1a).

Isotype: IgG1  (Matching secondary antibodies)

Description: HCV is a small 50nm, enveloped, single-stranded, positive sense RNA virus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).

Application Details

Application Notes: Suitable for use in ELISA, IFA and Western blot. Warning, This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1

Concentration: 1mg/ml in PBS (after reconstitution)

Buffer: 0.01M PBS, pH 7.2, with 0.1% Sodium azide. Stability: Upon arrival, aliquot and store at -20

Restrictions: For Research Use only