Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1) antibody

Antigen: Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1)

Synonyms: LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1, FLJ26167, CG12215, CG12915, CG33135, dKCNQ, DKCNQ, DmelCG33135, kcnq1, KCNQ1, kqt-3, kv7.1, Kvlqt1, kcnq1-A, KvLQT-1, xkvlqt1, zgc:158384

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN335144

Additional Information

Alternative name: KCNQ1

Gene ID: 3784

Immunogen: C-EQLTVPRRGPDEGS

Description: All names and symbols: KCNQ1, potassium voltage-gated channel, KQT-like subfamily, member 1, ATFB1, FLJ26167, JLNS1, KCNA8, KCNA9, KVLQT1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, WRS, Jervell and Lange-Nielsen syndrome 1, kidney and cardiac voltage dependend K+ channel, long (electrocardiographic) QT syndrome, Ward-Romano syndrome 1, slow delayed rectifier channel subunit. Official Symbol: KCNQ1. RefSeq number(s): NP_000209.2, NP_861463.1

Specificity: This antibody is expected to recognize both reported isoforms (NP_000209.2, NP_861463.1). Human, Dog

Synonyms: LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1, FLJ26167, CG12215, CG12915, CG33135, dKCNQ, DKCNQ, DmelCG33135, kcnq1, KCNQ1, kqt-3, kv7.1, Kvlqt1, kcnq1-A, KvLQT-1, xkvlqt1, zgc:158384

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx. 60kDa band observed in Human Heart lysates (calculated MW of 61.5kDa according to NP_861463.1). Recommended concentration: 1-3µg/ml. An additional band of unknown identity was also consistently observed at 28kDa. This band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any such results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Cardiovascular, Metabolism

Restrictions: For Research Use only

Images

EB09214 (1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.