anti-Vimentin antibody (VIM)

Details for Product anti-VIM Antibody No. ABIN335271
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms vime, CTRCT30, cb28, vim, vim1, vim2, VIM, Vimentin
Show less
Human, Mouse (Murine), Rat (Rattus), Hamster, Chicken, Goat, Dog (Canine), Monkey, Zebrafish (Danio rerio)
(630), (165), (152), (62), (46), (31), (20), (19), (9), (9), (8), (5), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
(327), (303), (30), (12), (11), (7), (5)
Clonality (Clone)
Monoclonal ()
This Vimentin antibody is un-conjugated
(23), (23), (13), (9), (7), (4), (3), (3), (3), (3), (3), (3), (3), (3), (1), (1), (1), (1)
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(513), (235), (198), (150), (116), (76), (76), (59), (47), (30), (16), (14), (13), (10), (4), (3), (3), (3), (3), (2), (1), (1)
Pubmed 5 references available
Quantity 1 mL
Shipping to United States ( )
Availability Will be delivered in 5 to 7 Business Days
Immunogen RV202 is a mouse monoclonal IgG1 antibody derived by fusion of SP2/0-Ag14 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with a cytoskeletal vimentin extract of calf lens.
Clone RV202
Isotype IgG1
Specificity Human, mouse, rat, hamster, chicken, goat, canine and monkey.
Purification Culture supernatant
Alternative Name Vimentin (VIM Antibody Abstract)
Background Vimentin (57 kDa) is the intermediate filament protein (IFP) of mesenchymal cells. This IFP however often deviates from the tissue-specific and developmentally regulated pattern of expression. Besides its typical expression in most cultured cells, vimentin is also expressed together with several other IFPs during early stages of development. As differentiation proceeds, vimentin is exchanged for the tissue-specific intermediate filament type. Also in cancers, vimentin is often expressed in addition to the tissue-specific IFP.
Research Area Lineage Markers, Cytoskeleton, Neural Stem Cell marker, Cell/Tissue Markers
Pathways TCR Signaling, Caspase Cascade in Apoptosis
Application Notes RV202 reacts exclusively with vimentin, which is expressed in mesenchymal cells and mesenchymal derived tumors e.g. lymphoma, sarcoma and melanoma. RV202 is suitable for immunoblotting, immunocytochemistry, immunohistochemistry on frozen tissues and for staining with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagentand flow cytometry. Optimal antibody dilution should be determined by titration.
Restrictions For Research Use only
Format Liquid
Storage 4 °C
Supplier Images
Image no. 1 for anti-Vimentin antibody (VIM) (ABIN335271) anti-Vimentin (VIM) antibody
Image no. 2 for anti-Vimentin antibody (VIM) (ABIN335271) anti-Vimentin (VIM) antibody (Image 2)
Background publications Pieper, Schaart, Krimpenfort et al.: "Transgenic expression of the muscle-specific intermediate filament protein desmin in nonmuscle cells." in: The Journal of cell biology, Vol. 108, Issue 3, pp. 1009-24, 1989 (PubMed).

Viebahn, Lane, Ramaekers: "Keratin and vimentin expression in early organogenesis of the rabbit embryo." in: Cell and tissue research, Vol. 253, Issue 3, pp. 553-62, 1988 (PubMed).

Ramaekers, Huysmans, Schaart et al.: "Tissue distribution of keratin 7 as monitored by a monoclonal antibody." in: Experimental cell research, Vol. 170, Issue 1, pp. 235-49, 1987 (PubMed).

Raats, Pieper, Vree Egberts et al.: "Assembly of amino-terminally deleted desmin in vimentin-free cells." in: The Journal of cell biology, Vol. 111, Issue 5 Pt 1, pp. 1971-85, 1990 (PubMed).

Ramaekers, van Niekerk, Poels et al.: "Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas." in: The American journal of pathology, Vol. 136, Issue 3, pp. 641-55, 1990 (PubMed).

Catalog No. ABIN335271
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?