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CD45 antibody (C-Term)

Name: CD45 antibody (C-Term)
SKU: ABIN337379
Price: 661.83 USD
Availability: InStock

PTPRC Reactivity: Human IHC, IHC (p) Host: Rabbit Polyclonal unconjugated

IHC

Human Thymus (formalin-fixed, paraffin-embedded) stained with CD45 antibody ABIN337379 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen.

IHC (p)

2 images

Catalog No. ABIN337379

Datasheet as PDF

Target See all CD45 (PTPRC) Antibodies

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
Binding Specificity
16

16

14

14

13

10

9

7

6

6

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reactivity
384

227

79

29

20

16

15

10

7

6

6

4

4

3

3

3

2

1

1

1

1

1

1
Human
Host
282

178

138

2

1

1
Rabbit
Compatible Secondaries
Clonality
466

128

1
Polyclonal
Conjugate
174

58

49

46

38

15

13

11

10

10

9

9

8

8

7

6

6

6

6

6

5

5

5

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1
This CD45 antibody is un-conjugated
Application
496

197

147

127

126

74

59

58

47

27

17

15

14

13

12

5

4

3

3

3

2

2

1

1

1

1

1

1
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand

IHC-plus™

Purification

Purified

Immunogen

Peptide derived from C-terminal sequence of human CD45.

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Application Notes

Approved: IHC, IHC-P (10 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

20 mM Tris-HCl,  pH 8.0, 20 mg/mL BSA, 0.05 % sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Aliquot to Avoid freeze/thaw cycles.

Storage

4 °C

Storage Comment

Store at 2-8°C. Do not freeze.
Target

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

Alternative Name

CD45 (PTPRC Products)

Synonyms

PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody

Background

Name/Gene ID: PTPRC
Subfamily: R1/R6
Family: Protein Phosphatase

Synonyms: PTPRC, B220, CD45R, CD45, gp180, Leukocyte common antigen, L-CA, Leucocyte common antigen, LY5, T200, T200 glycoprotein, T200 leukocyte common antigen, CD45 antigen, LCA

Gene ID

5788

UniProt

P08575

Pathways

TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling