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Antibodies
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anti-Desipramine/Nortriptyline antibody
Desipramine/Nortriptyline antibody
| Antigen |
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| Clonality |
Polyclonal |
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Host
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| Catalog no. |
ABIN343200 |
| Quantity |
1ml |
| Price |
234.51 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 3 to 5 Business Days |
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Immunogen
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Patented mixed immunogen
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Format
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Neat antiserum
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Description
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Both Desipramine and Nortriptyline are used as anti-depressants. Desipramine is a tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors. Nortriptyline is a metabolite of amitriptyline that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions. [PubChem]
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Specificity
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Desipramine 100% Nortryptiline 125% Amitryptiline 188% Imipramine 208% Maprotiline <1% Digoxin <1% Affinity constant: 5x109 L/mol (determined using 3H-nortriptyline)
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Buffer
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No Preservative
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Storage
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Store at -20°C. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody.
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Research Area
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Drugs
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Restrictions
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For Research Use only
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Alternatives for antigen "Desipramine/Nortriptyline", type "Antibodies"
Alternatives 
