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Glial Fibrillary Acidic Protein (GFAP) antibody

Antigen

Glial Fibrillary Acidic Protein (GFAP)
Synonyms GFAP, DKFZp459C0729, MGC139638, FLJ45472, AI836096, cb345, gfapl, MGC110485, wu:fb34h11, wu:fk42c12, zgc:110485, etID36982.3, xx:af506734
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Rat (Rattus), Mouse (Murine)
Application
Alternatives Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Catalog no. ABIN343361
Quantity 100ug  (Variants)
Price 283.33 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Alternative name Glial fibrillary acidic protein, GFAP
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human GFAP, identical to the related rat and mouse sequence.
Format Affinity-purified
Isotype IgG  (Matching secondary antibodies)
Description Glial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. 1 GFAP has been located in rat kidney glomeruli and peritubular fibroblasts, leydig cells of testis, skin keratinocytes, osteocytes of bones, chondrocytes of epiglottis, bronchus, and stellate-shaped cells of the pancreas and liver. Its expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination. 2 GFAP has also been shown to play a role in mitosis by adjusting the filament network present in the cell. During mitosis, there is an increase in the amount of phosphorylated GFAP, and a movement of this modified protein to the cleavage furrow. 3
Specificity Human, rat, mouse. No cross reactivity with other proteins.

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes WB 1ug/ml (Rat, Ms). IHC-P 2ug/ml (Hu, Rat, Ms). Antigen Retrieval by heat
Purity Immunogen affinity purified.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .
Storage At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "Glial Fibrillary Acidic Protein (GFAP)", type "Antibodies"
Hosts Mouse (151), Rabbit (82), Chicken (12), Goat (4), Guinea Pig (2)
Reactivities Human (162), Rat (Rattus) (64), Pig (Porcine) (62), Cow (Bovine) (46), Mouse (Murine) (45), Sheep (Ovine) (21), Rabbit (19), Dog (Canine) (18), Chicken (13), Guinea Pig (12), Mammalian (11), Cat (Feline) (8), Goat (3), Bird (Avian) (2), Caprinae (2), Hamster (1), Horse (Equine) (1), Monkey (1), Primate (1)
Applications Western Blotting (WB) (155), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (106), Immunofluorescence (IF) (99), Immunohistochemistry (Frozen Sections) (IHC (fro)) (62), Immunohistochemistry (IHC) (46), Immunoprecipitation (IP) (31), Flow Cytometry (FACS) (23), Immunocytochemistry (ICC) (21), ELISA (18), Enzyme Immunoassay (EIA) (16), ELISA (Detection) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Dot Blot (Dot) (1), ELISA (Capture) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (6), Cy3 (3), HRP (3), Alexa Fluor 488 (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes pSer8 (2), C-Term (1), internal (1)