Aquaporin 5 (AQP5) antibody

Antigen: Aquaporin 5 (AQP5)

Synonyms: MGC124967, MIP, AQP5, aqp2, LOC100231329

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat (Rattus), Mouse (Murine)

Application: Western Blotting (WB)

Catalog no.: ABIN343370

Additional Information

Alternative name: Aquaporin 5, AQP5

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human AQP5, different to the related rat sequence by three amino acids.

Format: Affinity-purified

Isotype: IgG  (Matching secondary antibodies)

Description: Aquaporin 5, also known as AQP5, is a water channel protein. The aquaporins (AQPs) are a family of more than 10 homologous water transporting proteins expressed in many mammalian epithelia and endothelia. At least five AQPs are expressed in the eye: AQP0 (MIP) in lens fiber, AQP1 in cornea endothelium, ciliary and lens epithelia and trabecular meshwork, AQP3 in conjunctiva, AQP4 in ciliary epithelium and retinal Müller cells, and AQP5 in corneal and lacrimal gland epithelia. 1 Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. 2 Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions.

Specificity: Rat, mouse No cross reactivity with other proteins.

Application Details

Application Notes: WB 1ug/ml (Rat, Ms)

Purity: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

Restrictions: For Research Use only