Patatin-Like phospholipase Domain Containing 6 (PNPLA6) antibody

Antigen: Patatin-Like phospholipase Domain Containing 6 (PNPLA6)

Synonyms: NTE, sws, SPG39, NTEMND

Clonality: Polyclonal

Host: Rabbit

Reactivity: Zebrafish (Danio rerio)

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Catalog no.: ABIN343374

Additional Information

Alternative name: Patatin-like phospholipase domain containing 6, PNPLA6

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of fish PNPLA6 (1323-1348 amino acid).

Format: Affinity-purified

Isotype: IgG  (Matching secondary antibodies)

Description: Patatin-like phospholipase domain containing 6 (PNPLA6), also known as Neuropathy target esterase (NTE), is a human gene. Neuropathy target esterase (NTE) is involved in neural development and is the target for neurodegeneration induced by selected organophosphorus pesticides and chemical warfare agents. The genetic or chemical reduction of Nte activity results in a neurological phenotype of hyperactivity in mammals and indicate that EOPF toxicity occurs directly through inhibition of Nte without the requirement for Nte gain of function or aging. 1

Specificity: Zebrafish. No cross reactivity with other proteins.

Application Details

Application Notes: WB 1ug/ml (Zebrafish), IHC-P 1-2ug/ml (Zebrafish), Enzyme Digestion IHC-F 1-2ug/ml (Zebrafish)

Purity: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

Restrictions: For Research Use only