Cyclin D2 (CCND2) antibody
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| Synonyms |
KIAK0002, MGC102758, cD2, Vin1, Vin-1, C86853, AI256817, BF642806, 2600016F06Rik, ccnd2-A, CCND2, si:ch211-240j22.2, MGC142404, MGC132398, ccnd2, kiak0002, LOC100224096 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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Immunofluorescence (IF) (25), Western Blotting (WB) (24), Flow Cytometry (FACS) (20), Immunoprecipitation (IP) (14), Immunohistochemistry (Frozen Sections) (IHC (fro)) (7), ELISA (4), ELISA (Detection) (4), Immunocytochemistry (ICC) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1)
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| Catalog no. |
ABIN343375 |
| Quantity |
100ug |
| Price |
283.33 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Alternative name
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Cyclin D2
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Immunogen
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A synthetic peptide corresponding to a sequence at the C-terminal of human Cyclin D2, identical to the related rat and mouse sequence.
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Format
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Affinity-purified
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Cyclin D2, also known as CCND2, is a human gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D1, Cyclin D2 and Cyclin D3 are the members of the cyclin family. Cyclin D2 mapped to 12p13 1 , since the CCND1 gene is on 11q13, this may be another bit of evidence of the homology of chromosomes 11 and 12. Choi D et al proved the expression of pseudogene cyclin D2 mRNA in the human ovary increases with age, which may be a novel marker for decreased ovarian function associated with the aging process. 2 And knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.
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Specificity
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Human, mouse, rat. No cross reactivity with other proteins.
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Application Notes
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WB 1ug/ml (Hu, Rat, Ms)
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Purity
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Immunogen affinity purified.
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Buffer
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Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .
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Storage
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At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.
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Research Area
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Cancer, Cell Cycle
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Restrictions
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For Research Use only
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Alternatives for antigen "Cyclin D2 (CCND2)", type "Antibodies"
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Hosts
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Rabbit (25), Mouse (21)
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Reactivities
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Human (41), Mouse (Murine) (24), Rat (Rattus) (21)
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Applications
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Immunofluorescence (IF) (25), Western Blotting (WB) (24), Flow Cytometry (FACS) (20), Immunoprecipitation (IP) (14), Immunohistochemistry (Frozen Sections) (IHC (fro)) (7), ELISA (4), ELISA (Detection) (4), Immunocytochemistry (ICC) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Enzyme Immunoassay (EIA) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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pThr280 (1)
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Alternatives 
