RAD51 Homolog Protein (RAD51) antibody

Antigen: RAD51 Homolog Protein (RAD51)

Synonyms: RECA, BRCC5, HRAD51, RAD51A, HsRad51, HsT16930, RAD51, CRAD51, MGC128559, CG7948, D37788, Dm Rad51, DmelCG7948, DMR, DMR/DroRAD51, DMR1, dmRAD51, Dmrad51, DmRad51, DmRAD51, RA51, rad51, Rad51, Rad51dm, Spn-A, spnA, MGC52570, MGC130792, zgc:77754, wu:fb38e12, RGD1563603, GB17143, spn-A, F22D1.20, F22D1_20, MUT5

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN343380

Additional Information

Alternative name: DNA repair protein RAD51 homolog 1, RAD51A

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human RAD51A, different from the related rat sequence by one amino acid.

Format: Affinity-purified

Isotype: IgG  (Matching secondary antibodies)

Description: DNA repair protein RAD51 homolog 1, also known as RAD51A, is a human gene. The Rad51 gene, HsRAD51, is a homolog of RecA of Escherichia coli and functions in recombination and DNA repair. BRCA1 and BRCA2 proteins form a complex with Rad51, and these genes are thought to participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. 1 RAD51 is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. 2

Specificity: Human, mouse, rat. No cross reactivity with other proteins.

Synonyms: RECA, BRCC5, HRAD51, RAD51A, HsRad51, HsT16930, RAD51, CRAD51, MGC128559, CG7948, D37788, Dm Rad51, DmelCG7948, DMR, DMR/DroRAD51, DMR1, dmRAD51, Dmrad51, DmRad51, DmRAD51, RA51, rad51, Rad51, Rad51dm, Spn-A, spnA, MGC52570, MGC130792, zgc:77754, wu:fb38e12, RGD1563603, GB17143, spn-A, F22D1.20, F22D1_20, MUT5

Application Details

Application Notes: WB 1ug/ml (Hu, Rat, Ms). IHC-P 1-2ug/ml (Hu, Rat, Ms). Antigen Retrieval by heat

Purity: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

Restrictions: For Research Use only