Notch 1 (NOTCH1) antibody

Antigen: Notch 1 (NOTCH1)

Synonyms: hN1, TAN1, Mis6, Tan1, lin-12, 9930111A19Rik, NOTCH, NOTCH1, notch1, hn1, tan1, notch, xotch, xnotch, notch-1, xnotch1

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN343383

Additional Information

Alternative name: NOTCH1

Immunogen: A synthetic peptide corresponding to a sequence at the middle region of human NOTCH1, different from the related rat sequence by one amino acid.

Format: Affinity-purified

Isotype: IgG  (Matching secondary antibodies)

Description: Notch proteins are single-pass transmembrane receptors that regulate cell fate decisions during development. The Notch family includes 4 receptors, NOTCH1, NOTCH2, NOTCH3, and NOTCH4, whose ligands include JAG1, JAG2, DLL1), DLL3, and DLL4. Notch homolog 1, translocation-associated (NOTCH1), is a human gene encoding a single-pass transmembrane receptor. It functions as a receptor for membrane bound ligands, and may play multiple roles during development. NOTCH1 may normally coordinates the process of somitogenesis, 1 and the activated Notch 1 and Notch 3 promote differentiation of progenitor cells into astroglia. 2

Specificity: Human. No cross reactivity with other proteins.

Application Details

Application Notes: WB 1ug/ml (Hu)

Purity: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

Research Area: Receptors, Signaling, Inflammation, Immunology

Restrictions: For Research Use only