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Antibodies
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anti-Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) ...
Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) antibody
| Antigen |
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| Synonyms |
LOC100219853, CD11C, SLEB6, Cr4, N418, Cd11c, AI449405, ITGAX, CD11c |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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Alternatives Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
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| Catalog no. |
ABIN343461 |
| Quantity |
100ug |
| Price |
283.33 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Alternative name
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Integrin alpha4, ITGA4
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Immunogen
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A synthetic peptide corresponding to the C-terminal of human ITGA4, identical to the related rat sequence.
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Format
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Affinity-purified
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Isotype
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IgG
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Description
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The integrin family includes cell surface receptors for extracellular matrix components as well as receptors involved in various aspects of leukocyte adhesion. Integrin alpha chain 4 (ITGA4) is assigned to 2q31-q32. Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia.
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Specificity
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Human, mouse, rat. No cross reactivity with other proteins.
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Application Notes
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Western blotting: At 1-2u/ml with the appropriate system to detect ITGA4 in cells and tissues. Immunohistochemistry (Paraffin-embedded Sections): At 1-2u/ml to detect ITGA4 in formalin fixed and paraffin embedded tissues. Boiling the sections is required. Immunocytochemistry At 2-4u/ml to detect ITGA4 in acetone fixed cell. Antigen retrieval by Pepsin and Trypsin is required. Other applications have not been tested. Optimal dilutions should be determined by end user.
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Purity
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Immunogen affinity purified.
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Buffer
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Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na 2 HPO 4 .
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Storage
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At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 1.2% sodium acetate or neutral PBS. If 0.5ml of PBS is used, the antibody concentration will be 100ug/ml.
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Restrictions
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For Research Use only
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Alternatives for antigen "Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4)", type "Antibodies"