Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) antibody

Antigen: Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3)

Synonyms: EA6, EAAT1, GLAST, GLAST1, FLJ25094, Gmt1, Eaat1, GLU-T, GluT-1, MGluT1, GLAST-1, AI504299, B430115D02Rik, AF001784, CG3747, dEAAT, dEaat1, dEAAT1, Dglt-1, Dglut-1, DmelCG3747, EAAT, MGC140731, zgc:56661, zgc:77768, wu:fb98e05, wu:fd50b05, SLC1A3

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN343469

Additional Information

Alternative name: Glast (EAAT1)

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of the human Glast, identical to the related rat sequence.

Format: Affinity-purified

Isotype: IgG  (Matching secondary antibodies)

Description: Glast, also known as EAAT1. EAAT1 (SLC1A3) is a member of a family of high-affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system. human GLAST1 gene contains 10 exons spanning at least 85 kb. EAAT1 gene is mapped to chromosome 5p13. GLAST is required for normal signal transmission between photoreceptors and bipolar cells and that both GLAST and GLT-1 play a neuroprotective role during ischemia in the retina. Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures.

Specificity: Human, mouse, rat. No cross reactivity with other proteins.

Synonyms: EA6, EAAT1, GLAST, GLAST1, FLJ25094, Gmt1, Eaat1, GLU-T, GluT-1, MGluT1, GLAST-1, AI504299, B430115D02Rik, AF001784, CG3747, dEAAT, dEaat1, dEAAT1, Dglt-1, Dglut-1, DmelCG3747, EAAT, MGC140731, zgc:56661, zgc:77768, wu:fb98e05, wu:fd50b05, SLC1A3

Application Details

Application Notes: Western blotting: At 0.5-1u/ml with the appropriate system to detect glast in cells and tissues. Other applications have not been tested. Optimal dilutions should be determined by end user.

Purity: Immunogen affinity purified.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na 2 HPO 4 , 0.05mg Thimerosal, 0.05mg NaN 3 .

Storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for longer time. Reconstitution: 0.2ml of distilled water will yield a concentration of 500ug/ml.

Restrictions: For Research Use only